DFDA

Azathioprine

Treatment for Inflammatory Bowel Disease

Typical Dosage: 2.0-2.5 mg/kg daily

Effectiveness
62%
Safety Score
35%
Clinical Trials
81
Participants
15K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
35
DangerousModerateSafe
Treatment Details
Dosage Range
2.0-2.5 mg/kg daily
Time to Effect
3-6 months
Treatment Duration
years
Evidence Quality
HIGH
Number Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
20(Treat 20 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$1,300
Side Effect Mgmt:$500
Total Annual:$2,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
ICER
$80,000/QALY
QALYs Gained
0.15
Outcome-Based Costs
Cost per Responder
$4,444
Cost per Remission
$8,000
Azathioprine Outcomes

for Inflammatory Bowel Disease

Efficacy Outcomes
Overall Effectiveness
+62%
Response Rate
+45%
Remission Rate
+25%
Common Side Effects
Nausea/vomiting
+12%
Pancreatitis
+5%
Leukopenia/Thrombocytopenia
+3%
Hepatotoxicity
+2%
Infections
+7%

Sources:

nih.gov
nih.gov
ku.dk

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
2 active trials recruiting for Azathioprine in Inflammatory Bowel Disease

Medical Treatment Versus Surgery in Stricturing Small Bowel Crohn's Disease

NCT05584228NOT YET RECRUITINGNA
View Study
150 participants
INTERVENTIONAL
Started: Apr 1, 2023

HLADQA1*05 Genotype and the Efficacy of Treatment With Infliximab in Chinese Population Crohn's Disease

NCT05813860NOT YET RECRUITINGPHASE4
View Study
976 participants
INTERVENTIONAL
Started: Apr 30, 2023
Completed Clinical Trials
8 completed trials for Azathioprine in Inflammatory Bowel Disease

Azathioprine & Allopurinol in Inflammatory Bowel Disease Patients

NCT00849368COMPLETEDPHASE1
View Study
6 participants
INTERVENTIONAL
Zurich, Switzerland
Started: Jan 1, 2009

Abdominal Ultrasound With Doppler and Peripheral Hemogram in Assesment Inflammatory Bowel Disease

NCT03445624COMPLETED
View Study
60 participants
OBSERVATIONAL
Asyut, Egypt
Started: Jul 1, 2018

Azathioprine Linked With Impaired Intestinal Epithelial Postoperative Regeneration in Crohn's Disease

NCT05456776COMPLETED
View Study
35 participants
OBSERVATIONAL
Started: Apr 1, 2014

Chronotherapy in Inflammatory Bowel Disease

NCT04304950COMPLETEDPHASE4
View Study
28 participants
INTERVENTIONAL
Chicago, United States
Started: Apr 25, 2016

Efficacy of LiveSpo COLON as a Supportive Treatment for Inflammatory Bowel Disease (IBD)

NCT06637683COMPLETEDNA
View Study
60 participants
INTERVENTIONAL
Thái Bình, Vietnam
Started: Nov 15, 2019

Preventing Postoperative Relapse in Crohn's Disease Patients at Risk: Azathioprine Versus Mesalazine

NCT00946946COMPLETEDPHASE3
View Study
78 participants
INTERVENTIONAL
Vienna, Austria +1 more
Started: Feb 1, 2002

Immunogenicity of Influenza, Pneumococcal and Hepatitis B Vaccines in IBD Patients Treated With Vedolizumab

NCT03056924COMPLETED
View Study
173 participants
OBSERVATIONAL
Boston, United States
Started: Jul 5, 2017

Cost-effectiveness of TPMT Pharmacogenetics

NCT00521950COMPLETEDNA
View Study
853 participants
INTERVENTIONAL
Nijmegen, Netherlands +2 more
Started: Sep 1, 2007
Showing 20 of 83 total trials