Doxepin (low-dose)
Treatment for Insomnia
Typical Dosage: 3-6 mg at bedtime
Effectiveness
60%
Safety Score
60%
Clinical Trials
35
Participants
7.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
3-6 mg at bedtime
Time to Effect
1-2 hours
Treatment Duration
long-term
Evidence Quality
HIGHNumber Needed to Treat (NNT)
10(Treat 10 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
40(Treat 40 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$75
Monitoring:$150
Side Effect Mgmt:$20
Total Annual:$245
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$60,000/QALY
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$445
Cost per Remission
$3,062
Doxepin (low-dose) Outcomes
for Insomnia
Efficacy Outcomes
Overall Effectiveness
+60%
Response Rate
+55%
Remission Rate
+8%
Common Side Effects
Somnolence
+5%
Nausea
+2%
Dizziness
+2%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov