Eszopiclone
Treatment for Insomnia
Typical Dosage: 1-3 mg at bedtime
Effectiveness
68%
Safety Score
45%
Clinical Trials
48
Participants
16K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
45
DangerousModerateSafe
Treatment Details
Dosage Range
1-3 mg at bedtime
Time to Effect
immediate
Treatment Duration
short-term (2-4 weeks), approved for longer
Evidence Quality
HIGHNumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
18(Treat 18 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100
Monitoring:$150
Side Effect Mgmt:$50
Total Annual:$300
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$100,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$500
Cost per Remission
$2,500
Eszopiclone Outcomes
for Insomnia
Efficacy Outcomes
Overall Effectiveness
+68%
Response Rate
+60%
Remission Rate
+12%
Common Side Effects
Unpleasant taste
+25%
Headache
+13%
Drowsiness
+12%
Dizziness
+7%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
19 completed trials for Eszopiclone in Insomnia
Investigation of the Safety and Efficacy of Eszopiclone in Insomnia Patients
NCT02452684COMPLETED
4.88K participants
OBSERVATIONAL
Osaka, Japan +1 more
Started: Oct 1, 2012
Investigation of the Safety and Efficacy of Long Term Administration of Eszopiclone in Insomnia Patients
NCT02455271COMPLETED
438 participants
OBSERVATIONAL
Osaka, Japan +1 more
Started: Oct 1, 2012
Eszopiclone Treatment & Cortisol Responsivity
NCT00889200COMPLETEDPHASE4
12 participants
INTERVENTIONAL
Providence, United States
Started: May 1, 2007
A Long-Term Safety and Efficacy Study of Eszopiclone in Elderly With Primary Chronic Insomnia
NCT00386334COMPLETEDPHASE4
388 participants
INTERVENTIONAL
Birmingham, United States +81 more
Started: Oct 1, 2006
Study of Eszopiclone Compared to Placebo in the Treatment of Insomnia Secondary to Perimenopause/Menopause
NCT00366093COMPLETEDPHASE3
410 participants
INTERVENTIONAL
Mobile, United States +50 more
Started: Feb 1, 2004
A Non-inferiority Study With Two Treatment Arms Eszopiclone 3 mg Versus Zopiclone 7.5 mg - for the Treatment of Insomnia
NCT01100164COMPLETEDPHASE3
263 participants
INTERVENTIONAL
São Paulo, Brazil
Started: Mar 1, 2011
Eszopiclone in the Treatment of Insomnia and Fibromyalgia
NCT00392041COMPLETEDPHASE4
36 participants
INTERVENTIONAL
Piscataway, United States
Started: Aug 1, 2006
Study of an Evening Dose of Eszopiclone on Next Day Driving Ability & Psychomotor/Memory Function in Healthy Volunteers
NCT00368160COMPLETEDPHASE1
32 participants
INTERVENTIONAL
Guildford, United Kingdom
Started: Mar 1, 2004
Treatment of Insomnia in Migraineurs
NCT00812214COMPLETEDPHASE4
113 participants
INTERVENTIONAL
Started: Apr 1, 2007
Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia
NCT00857220COMPLETEDPHASE3
304 participants
INTERVENTIONAL
Tucson, United States +88 more
Started: May 1, 2009
Modified Suanzaoren Decoction Versus Eszopiclone for the Treatment of Chronic Insomnia Disorder
NCT06452953COMPLETEDNA
85 participants
INTERVENTIONAL
Changsha, China
Started: Sep 10, 2020
Insomnia and Osteoarthritis Study
NCT00374556COMPLETEDNA
30 participants
INTERVENTIONAL
Baltimore, United States
Started: Jan 1, 2006
Safety & Efficacy Study of Study Drug (Eszopiclone) in Children and Adolescents With Attention-deficit/Hyperactivity Disorder - Associated Insomnia
NCT00856973COMPLETEDPHASE3
486 participants
INTERVENTIONAL
Birmingham, United States +72 more
Started: May 1, 2009
Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder
NCT00813735COMPLETEDPHASE4
60 participants
INTERVENTIONAL
Allentown, United States
Started: Sep 1, 2006
Study of the Insomnia in Patients With Low Back Pain
NCT00365976COMPLETEDPHASE4
58 participants
INTERVENTIONAL
Durham, United States
Started: Aug 1, 2006
The Effects of Eszopiclone and Lexapro on Prefrontal Glutamate and GABA in Depression With Anxiety and Insomnia
NCT00826111COMPLETEDPHASE4
19 participants
INTERVENTIONAL
Boston, United States
Started: Aug 1, 2007
6-Month Chronic Efficacy & Safety Study of Eszopiclone in Adult Subjects With Primary Insomnia
NCT00352144COMPLETEDPHASE3
830 participants
INTERVENTIONAL
Birmingham, United States +57 more
Started: Oct 1, 2003
Treatment of Insomnia in Patients With Parkinson's Disease: A Multi-site, Placebo-controlled Study of Eszopiclone
NCT00324896COMPLETEDPHASE3
30 participants
INTERVENTIONAL
Suwanee, United States +3 more
Started: May 1, 2006
A Bioequivalence and Food Effect Study of SEP-190 in Japanese Healthy Subjects (Study SEP 190-102)
NCT01055834COMPLETEDPHASE1
42 participants
INTERVENTIONAL
Sumida City, Japan
Started: Jan 1, 2010
Showing 20 of 48 total trials