Oral Ferrous Sulfate
Treatment for Iron Deficiency Anemia
Typical Dosage: 65-195 mg elemental iron daily
Effectiveness
85%
Safety Score
78%
Clinical Trials
137
Participants
5M
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
78
DangerousModerateSafe
Treatment Details
Dosage Range
65-195 mg elemental iron daily
Time to Effect
1-3 months for full correction
Treatment Duration
3-6 months
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$20
Monitoring:$400
Side Effect Mgmt:$50
Total Annual:$470
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$1,000/QALY
QALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$627
Cost per Remission
$723
Oral Ferrous Sulfate Outcomes
for Iron Deficiency Anemia
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+75%
Remission Rate
+65%
Common Side Effects
Dark stools
+100%
Constipation
+25%
Nausea/Abdominal pain
+20%
Diarrhea
+8%
Sources:
Active Clinical Trials
4 active trials recruiting for Oral Ferrous Sulfate in Iron Deficiency Anemia
Impact of Intravenous Iron on Musculoskeletal Function in Older Adults
NCT05708170NOT YET RECRUITINGPHASE4
100 participants
INTERVENTIONAL
Started: Jan 1, 2023
Comparison Of Efficacy Of Iron Polymaltose Complex And Ferrous Sulphate In Iron Deficiency Anemia In Pediatric Patients
NCT06742528RECRUITINGNA
198 participants
INTERVENTIONAL
Peshawar, Pakistan
Started: Jan 10, 2024
Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy
NCT05462704RECRUITINGPHASE3
300 participants
INTERVENTIONAL
Birmingham, United States +7 more
Started: Jan 17, 2023
Daily Iron vs Every-other-day Iron for Pediatric Patients With IDA
NCT06550362NOT YET RECRUITINGPHASE4
100 participants
INTERVENTIONAL
Started: Dec 1, 2025
Completed Clinical Trials
15 completed trials for Oral Ferrous Sulfate in Iron Deficiency Anemia
Effectiveness of Oral Iron Therapy in Iron Deficiency Anemia With Daily vs Alternate Day Dosing
NCT07267975COMPLETEDPHASE3
60 participants
INTERVENTIONAL
Lahore, Pakistan
Started: Jan 7, 2025
Oral Iron Versus Oral Iron Plus a Web-based Behavioral Intervention in Young Children (IRONCHILD)
NCT04371536COMPLETEDPHASE3
1 participants
INTERVENTIONAL
Houston, United States
Started: Jul 9, 2021
Intravenous Iron Carboxymaltose, Isomaltoside and Oral Iron Sulphate for Postpartum Anemia
NCT03957057COMPLETEDPHASE3
300 participants
INTERVENTIONAL
Ljubljana, Slovenia
Started: Sep 10, 2020
Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies
NCT01221844COMPLETEDPHASE4
300 participants
INTERVENTIONAL
Rome, Italy
Started: Feb 1, 2010
Ferrous Acetyl-Aspartate Casein Formulation Evaluation Over Ferrous Sulfate in Iron Deficiency Anemia
NCT03524651COMPLETEDPHASE4
60 participants
INTERVENTIONAL
Athens, Greece +2 more
Started: May 2, 2018
Multicenter Randomized Active-controlled Study to Investigate Efficacy & Safety of IV FCM in Pediatric Patients With IDA
NCT03523117COMPLETEDPHASE3
79 participants
INTERVENTIONAL
Little Rock, United States +15 more
Started: Jan 31, 2019
Evaluate the Safety and Efficacy of Ferric Maltol Oral Suspension vs. Ferrous Sulfate Oral Liquid in Children and Adolescents Aged 2 to 17 Years With Iron-deficiency Anaemia, With a Single Arm Study in Infants Aged 1 Month to Less Than 2 Years
NCT05126901COMPLETEDPHASE3
65 participants
INTERVENTIONAL
Saraland, United States +22 more
Started: Nov 3, 2021
The Effect of Iron Deficiency Anemia During Pregnancy
NCT02590224COMPLETEDPHASE4
200 participants
INTERVENTIONAL
Asyut, Egypt
Started: Jan 1, 2016
Iron Infusion Into a Vein Compared to Iron Tablet Taken by Mouth for Treating Iron Deficiency Anemia in Pregnancy (IVON)
NCT04976179COMPLETEDPHASE3
1.06K participants
INTERVENTIONAL
Gwarzo, Nigeria +10 more
Started: Aug 9, 2021
Iron Absorption From Iron-enriched Aspergillus Oryzae
NCT03156712COMPLETEDNA
17 participants
INTERVENTIONAL
Ames, United States
Started: May 29, 2013
Iron Supplementation and Side Effects
NCT04018300COMPLETEDNA
17 participants
INTERVENTIONAL
Ames, United States
Started: Jan 8, 2018
Comparative Efficacy and Safety of Intravenous Ferric Carboxymaltose (FCM) Versus Oral Iron for Iron Deficiency Anaemia in Pregnant Women
NCT01131624COMPLETEDPHASE3
252 participants
INTERVENTIONAL
Epping, Australia +19 more
Started: May 1, 2010
Daily vs. Every Other Day Oral Iron Supplementation in Patients With Absolute Iron Deficiency Anemia
NCT03725384COMPLETEDPHASE3
51 participants
INTERVENTIONAL
Toronto, Canada +1 more
Started: Jan 4, 2019
Lactoferrin Efficacy Versus Ferrous Sulfate in Treatment of Patients With Iron Deficiency Anemia
NCT04267653COMPLETEDPHASE4
96 participants
INTERVENTIONAL
Asyut, Egypt
Started: Jan 1, 2018
Effect of Ferrous iROn and cUrcumin sTatus on Inflammatory and Neurotrophic markErs
NCT04465851COMPLETEDNA
155 participants
INTERVENTIONAL
London, United Kingdom
Started: Jul 18, 2018
Showing 20 of 139 total trials