Atorvastatin (Statin Therapy)
Treatment for Ischemic Stroke
Typical Dosage: 10-80 mg daily
Effectiveness
70%
Safety Score
65%
Clinical Trials
24
Participants
200K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
10-80 mg daily
Time to Effect
months to years
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
25(Treat 25 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
250(Treat 250 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$100
Side Effect Mgmt:$100
Total Annual:$250
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$5,000/QALY
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$1,000
Comparison vs Placebo
Cost Difference
+$250/year
More expensive
QALY Difference
+0.50 QALYs
Better outcomes
Dominance
No dominance
Atorvastatin (Statin Therapy) Outcomes
for Ischemic Stroke
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+25%
Common Side Effects
Myalgia
+7%
Liver enzyme elevation (non-serious)
+2%
New-onset diabetes
+0.8%
Sources:
Active Clinical Trials
9 active trials recruiting for Atorvastatin (Statin Therapy) in Ischemic Stroke
Statins in Frail Older Patients with Ischemic Stroke or Transient Ischemic Attack - the Prospective Cohort Study
NCT06785740RECRUITING
300 participants
OBSERVATIONAL
Almere Stad, Netherlands +3 more
Started: Nov 1, 2024
Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With Atherosclerosis
NCT07307989RECRUITINGPHASE2
300 participants
INTERVENTIONAL
Pozi, Taiwan
Started: Aug 1, 2025
Intracranial Hemorrhage Risk of Intensive Statin in Acute Ischemic Stroke With Cerebral Microbleeds
NCT05589454NOT YET RECRUITINGPHASE4
344 participants
INTERVENTIONAL
Chongqing, China +4 more
Started: Jan 1, 2023
StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial
NCT06785727NOT YET RECRUITINGPHASE4
612 participants
INTERVENTIONAL
Started: Feb 1, 2025
The Effect of InTensive Statin in Ischemic Stroke With inTracranial Atherosclerotic Plaques
NCT03753555RECRUITINGPHASE4
100 participants
INTERVENTIONAL
Shenyang, China
Started: Dec 1, 2018
Efficacy and Safety of Early Combined Therapy with PCSK9 Inhibitors and Statins in Acute Ischemic Stroke
NCT06696820RECRUITINGPHASE4
416 participants
INTERVENTIONAL
Wuhan, China +1 more
Started: Nov 29, 2024
Efficacy of Probucol Combined with Statins Treatment for Ischemic Stroke
NCT06604117RECRUITING
200 participants
OBSERVATIONAL
Xicheng District, China
Started: Oct 17, 2024
Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke
NCT07301372RECRUITINGPHASE4
132 participants
INTERVENTIONAL
Xuzhou, China
Started: Oct 30, 2025
Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
NCT04847752RECRUITING
1K participants
OBSERVATIONAL
Wuhan, China
Started: Mar 1, 2021
Completed Clinical Trials
4 completed trials for Atorvastatin (Statin Therapy) in Ischemic Stroke
AdminiStration of Statin On Acute Ischemic stRoke patienT Trial
NCT02549846COMPLETEDPHASE4
270 participants
INTERVENTIONAL
Nishinomiya, Japan
Started: Sep 1, 2015
The Safety and Efficacy Study of High Dose Atorvastatin After Thrombolytic Treatment in Acute Ischemic Stroke
NCT02452502COMPLETEDNA
254 participants
INTERVENTIONAL
Changchun, China +1 more
Started: Sep 2, 2015
Real World Evidence Study of Statin Use in Brazil
NCT05285085COMPLETED
2.13M participants
OBSERVATIONAL
São Paulo, Brazil
Started: Nov 19, 2021
Standard Medical Management in Secondary Prevention of Ischemic Stroke in China
NCT00664846COMPLETEDNA
4K participants
INTERVENTIONAL
Beijing, China +45 more
Started: Apr 1, 2008
Showing 20 of 26 total trials