Percutaneous Nephrolithotomy (PCNL)
Treatment for Kidney Stones
Effectiveness
95%
Safety Score
45%
Clinical Trials
79
Participants
45K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
45
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate stone removal
Treatment Duration
Single procedure (hospitalization 2-4 days)
Evidence Quality
HIGHConfidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$2,000
Side Effect Mgmt:$1,500
Total Annual:$15,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$85,000/QALY
QALYs Gained
0.9
Outcome-Based Costs
Cost per Responder
$15,789
Cost per Remission
$16,667
Active Clinical Trials
7 active trials recruiting for Percutaneous Nephrolithotomy (PCNL) in Kidney Stones
Supine vs. Prone PCNL for Large Renal Stones: A Randomized Trial in Yemen.
NCT07627503NOT YET RECRUITINGNA
140 participants
INTERVENTIONAL
Sanaa, Yemen
Started: Jun 1, 2026
Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones
NCT06922006ACTIVE NOT RECRUITING
67 participants
OBSERVATIONAL
San Diego, United States
Started: Mar 26, 2024
Safety and Effectiveness of Antegrade Flexible Ureteroscopy-Assisted Percutaneous Nephrolithotomy for Staghorn Calculi
NCT07172373NOT YET RECRUITINGNA
420 participants
INTERVENTIONAL
Started: Oct 1, 2025
PCNL Versus RIRS for Management of Stones in Solitary Kidney
NCT07730892ACTIVE NOT RECRUITINGNA
83 participants
INTERVENTIONAL
Al Mansurah, Egypt
Started: Nov 23, 2024
VISOR Versus PCNL for Treatment of 2-4cm Renal Stones
NCT07159503ENROLLING BY INVITATIONNA
170 participants
INTERVENTIONAL
Hangzhou, China
Started: Apr 20, 2025
FANS-Assisted Mini-PCNL for Complex Renal Stones
NCT07332286ACTIVE NOT RECRUITINGNA
30 participants
INTERVENTIONAL
Guangzhou, China
Started: Dec 19, 2025
Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy
NCT07393711NOT YET RECRUITINGNA
95 participants
INTERVENTIONAL
Aqtöbe, Kazakhstan
Started: Mar 1, 2026
Completed Clinical Trials
9 completed trials for Percutaneous Nephrolithotomy (PCNL) in Kidney Stones
Tubeless vs Tube PCNL in Pediatric Nephrolithiasis
NCT07183930COMPLETEDNA
640 participants
INTERVENTIONAL
Peshawar, Pakistan
Started: Oct 1, 2024
Comparison of Tubeless Versus Standard Percutaneous Nephrolithotomy (PCNL) for Renal Stones
NCT07522619COMPLETEDNA
60 participants
INTERVENTIONAL
Karachi, Pakistan
Started: Nov 24, 2021
Standard vs Mini-PCNL for the Treatment of Stone Disease
NCT04069013COMPLETEDNA
18 participants
INTERVENTIONAL
Cleveland, United States
Started: May 1, 2022
IAU Percutaneous Nephrolithotripsy Study
NCT07622238COMPLETED
4K participants
OBSERVATIONAL
Sofia, Bulgaria +1 more
Started: Aug 15, 2019
Suction Mini-PCNL Versus Standard PCNL for the Management of 2-4cm Kidney Stones
NCT05088213COMPLETEDNA
960 participants
INTERVENTIONAL
Guangzhou, China
Started: Dec 1, 2021
Comparison of Trifecta Analysis of Standard Versus Mini Percutaneous Nephrolithotomy in the Management of Urolithiasis
NCT06836700COMPLETEDNA
180 participants
INTERVENTIONAL
Peshawar, Pakistan
Started: Jan 10, 2022
Preoperative Anxiety in Patients Undergoing RIRS and PCNL
NCT07772830COMPLETED
120 participants
OBSERVATIONAL
Samsun, Turkey (Türkiye)
Started: Jan 20, 2024
Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithotomy Infectious Complications and Sepsis.
NCT07355907COMPLETEDNA
210 participants
INTERVENTIONAL
Tanta, Egypt
Started: Jan 1, 2023
Flexible Ureteroscopy With a Flexible and Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for 1-2 cm Lower Pole Kidney Stones
NCT07159035COMPLETEDNA
640 participants
INTERVENTIONAL
Guangzhou, China
Started: Aug 28, 2025
Showing 20 of 110 total trials