Tamsulosin
Treatment for Kidney Stones
Typical Dosage: 0.4mg daily
Effectiveness
75%
Safety Score
70%
Clinical Trials
23
Participants
25K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
0.4mg daily
Time to Effect
1-2 days (expulsion within 2-4 weeks)
Treatment Duration
2-4 weeks
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100
Monitoring:$300
Side Effect Mgmt:$50
Total Annual:$450
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.15
Outcome-Based Costs
Cost per Responder
$600
Cost per Remission
$600
Prescription Access Economics
Annual Societal Loss per Patient
$265
Cost of prescription-only barriers (visits, time, admin, price premium)
Physician Visit Cost
$125/year
Time Cost
$50/year
Travel + wait time
Insurance Admin Cost
$20/year
Prior auth, claims
Rx Price
$100/year
Potential OTC Price
$30/year
Estimated if OTC available
Early Treatment Benefit
+0.10 QALYs
From faster OTC access
Risk Assessment
Misuse Risk
LOWMissed Diagnosis Risk
LOWTamsulosin Outcomes
for Kidney Stones
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+75%
Remission Rate
+75%
Common Side Effects
Dizziness/Orthostatic Hypotension
+15%
Ejaculatory dysfunction
+10%
Headache
+7%
Sources:
Active Clinical Trials
1 active trial recruiting for Tamsulosin in Kidney Stones
Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure
NCT05100017RECRUITINGNA
126 participants
INTERVENTIONAL
Chicago, United States
Started: Sep 30, 2021
Completed Clinical Trials
9 completed trials for Tamsulosin in Kidney Stones
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
NCT00448123COMPLETEDNA
127 participants
INTERVENTIONAL
Royal Oak, United States
Started: Feb 1, 2007
Tamsulosin as Adjunctive Therapy After Extracorporeal Shock Wave Lithotripsy for Renal Stones
NCT04819828COMPLETEDPHASE4
60 participants
INTERVENTIONAL
Started: Jan 1, 2010
Ureteral Stent-related Pain and Mirabegron (SPAM) Trial
NCT02095665COMPLETEDPHASE4
22 participants
INTERVENTIONAL
Halifax, Canada
Started: Jan 1, 2014
Medical Expulsive Therapy Post-SWL For Renal Stones
NCT05032287COMPLETEDNA
235 participants
INTERVENTIONAL
Al Mansurah, Egypt
Started: Sep 1, 2019
Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy
NCT05725122COMPLETEDNA
82 participants
INTERVENTIONAL
Lahore, Pakistan
Started: Feb 1, 2018
Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis
NCT00762424COMPLETEDNA
53 participants
INTERVENTIONAL
York, United States
Started: Jun 1, 2007
THE EFFECTS OF MIRABEGRON AND TAMSULOSIN FOR PATIENTS WITH URETERAL STENTS
NCT06124066COMPLETEDPHASE4
42 participants
INTERVENTIONAL
Makassar, Indonesia
Started: Jul 1, 2022
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
NCT00600405COMPLETEDNA
81 participants
INTERVENTIONAL
Portland, United States
Started: Aug 1, 2006
Tamsulosin for Urolithiasis in the Emergency Dept
NCT00382265COMPLETEDPHASE4
512 participants
INTERVENTIONAL
Birmingham, United States +3 more
Started: Jan 1, 2008
Showing 20 of 22 total trials