Carbidopa/Levodopa
Treatment for Lewy Body Dementia
Typical Dosage: Typically 25/100 mg 3-4 times daily, titrated
Effectiveness
65%
Safety Score
55%
Clinical Trials
55
Participants
10.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
Typically 25/100 mg 3-4 times daily, titrated
Time to Effect
Days to weeks
Treatment Duration
lifetime
Evidence Quality
MODERATENumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
7(Treat 7 patients to see 1 additional serious adverse event)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100
Monitoring:$750
Side Effect Mgmt:$350
Total Annual:$1,200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$17,143/QALY
QALYs Gained
0.07
Outcome-Based Costs
Cost per Responder
$4,000
Carbidopa/Levodopa Outcomes
for Lewy Body Dementia
Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+30%
Common Side Effects
Nausea
+15%
Orthostatic hypotension
+15%
Hallucinations/Delusions
+20%
Dyskinesia
+12%
Dizziness
+8%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov