Cognitive Rehabilitation Therapy
Treatment for Long Covid
Typical Dosage: Individualized sessions, home exercises, 30-60 minutes daily
Effectiveness
55%
Safety Score
95%
Clinical Trials
29
Participants
1.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
Individualized sessions, home exercises, 30-60 minutes daily
Time to Effect
4-8 weeks
Treatment Duration
8-16 weeks, or ongoing as needed
Evidence Quality
MODERATEConfidence Score
65%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$2,000
Side Effect Mgmt:$0
Total Annual:$2,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.15
Outcome-Based Costs
Cost per Responder
$3,636.36
Cognitive Rehabilitation Therapy Outcomes
for Long Covid
Efficacy Outcomes
Overall Effectiveness
+55%
Response Rate
+55%
Remission Rate
+12%
Common Side Effects
Frustration/Mental fatigue
+12%
Limited improvement in severe cases
+7%
Sources:
Active Clinical Trials
8 active trials recruiting for Cognitive Rehabilitation Therapy in Long Covid
Cognitive Rehabilitation for People With Cognitive Covid19
NCT05731570ACTIVE NOT RECRUITINGNA
78 participants
INTERVENTIONAL
London, United Kingdom
Started: Feb 14, 2023
Cognitive Rehabilitation Therapy for COVID-19
NCT06086379ENROLLING BY INVITATIONNA
70 participants
INTERVENTIONAL
San Diego, United States
Started: Jul 1, 2024
tDCS in the Management of Post-COVID Disorders
NCT06074848RECRUITINGPHASE2
48 participants
INTERVENTIONAL
Recife, Brazil +1 more
Started: Aug 25, 2023
Evaluating the Impact of a Functional and Cognitive Strategy in Patients with Long Covid-19
NCT06871293NOT YET RECRUITINGNA
374 participants
INTERVENTIONAL
Bogotá DC, Colombia
Started: Apr 1, 2025
Long COVID Brain Fog: Cognitive Rehabilitation Trial
NCT06095297RECRUITINGNA
30 participants
INTERVENTIONAL
Birmingham, United States
Started: Apr 25, 2024
Design and Validation of Innovative Strategies Based on Dual-Task Approach
NCT07254377ACTIVE NOT RECRUITINGNA
48 participants
INTERVENTIONAL
Roma, Italy
Started: Nov 1, 2025
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
NCT05855369RECRUITINGPHASE2, PHASE3
180 participants
INTERVENTIONAL
Charleston, United States
Started: Oct 2, 2023
Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial
NCT06156176RECRUITINGNA
60 participants
INTERVENTIONAL
London, Canada
Started: Apr 1, 2025
Completed Clinical Trials
6 completed trials for Cognitive Rehabilitation Therapy in Long Covid
Cognitive Rehabilitation for Long COVID
NCT05676047COMPLETEDNA
100 participants
INTERVENTIONAL
Hamilton, Canada
Started: May 1, 2023
Multi-systemic Rehabilitative Interventions in Long COVID-19 Patients in Two Different Settings: a Randomized Controlled Trial
NCT06379737COMPLETEDNA
72 participants
INTERVENTIONAL
Padua, Italy
Started: Jan 1, 2023
RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Long COVID Symptoms
NCT05965752COMPLETEDNA
328 participants
INTERVENTIONAL
Phoenix, United States +23 more
Started: Sep 1, 2023
RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS Interventions on Long COVID Symptoms
NCT05965739COMPLETEDNA
328 participants
INTERVENTIONAL
Durham, United States
Started: Sep 1, 2023
Treatment of COVID-19 Post-acute Cognitive Impairment Sequelae With tDCS
NCT05389592COMPLETEDNA
60 participants
INTERVENTIONAL
São Paulo, Brazil
Started: Jun 30, 2022
Computer Cognitive Training for Post-acute COVID-19 Syndrome
NCT05338749COMPLETEDNA
16 participants
INTERVENTIONAL
Fort Lauderdale, United States
Started: Apr 26, 2022
Showing 20 of 30 total trials