Atorvastatin (Statin Therapy)
Treatment for Lower Extremity Peripheral Arterial Disease
Typical Dosage: 10-80mg daily
Effectiveness
60%
Safety Score
65%
Clinical Trials
1
Participants
500K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
10-80mg daily
Time to Effect
Months for clinical benefits (CV event reduction)
Treatment Duration
Lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
15(Treat 15 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
1000(Treat 1000 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$100
Side Effect Mgmt:$50
Total Annual:$200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$8,000/QALY
QALYs Gained
0.25
Outcome-Based Costs
Cost per Responder
$250
Atorvastatin (Statin Therapy) Outcomes
for Lower Extremity Peripheral Arterial Disease
Efficacy Outcomes
Overall Effectiveness
+60%
Response Rate
+80%
Common Side Effects
Myalgia (muscle pain)
+5%
Elevated liver enzymes
+2%
Rhabdomyolysis (rare)
+0.01%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
1 completed trial for Atorvastatin (Statin Therapy) in Lower Extremity Peripheral Arterial Disease
Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)
NCT00687076COMPLETEDPHASE4
102 participants
INTERVENTIONAL
Houston, United States
Started: Apr 1, 2004