DFDA

Surgical Revascularization (Bypass Surgery)

Treatment for Lower Extremity Peripheral Arterial Disease

Typical Dosage: N/A

Effectiveness
88%
Safety Score
55%
Clinical Trials
9
Participants
30K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
N/A
Time to Effect
Immediate to weeks
Treatment Duration
Single procedure, ongoing monitoring/potential re-interventions
Evidence Quality
MODERATE
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$500
Side Effect Mgmt:$500
Total Annual:$6,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
ICER
$95,000/QALY
QALYs Gained
0.45
Outcome-Based Costs
Cost per Responder
$7,059
Cost per Remission
$8,000
Comparison vs Endovascular Revascularization
Cost Difference
+$1,000/year
More expensive
QALY Difference
+0.10 QALYs
Better outcomes
Dominance
No dominance
Surgical Revascularization (Bypass Surgery) Outcomes

for Lower Extremity Peripheral Arterial Disease

Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+85%
Remission Rate
+75%
Common Side Effects
Surgical site infection
+10%
Bleeding/Hematoma
+8%
Graft thrombosis/failure
+20%
Cardiac complications (MI, arrhythmia)
+7%
Stroke
+3%
Mortality
+2%

Sources:

nih.gov
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
3 active trials recruiting for Surgical Revascularization (Bypass Surgery) in Lower Extremity Peripheral Arterial Disease

Evaluation of Tissue Perfusion in Peripheral Arterial Disease (EVTI-PAD)

NCT05570019RECRUITING
View Study
200 participants
OBSERVATIONAL
Innsbruck, Austria
Started: Oct 1, 2022

Prospective Case-control Study in Patients With PAA

NCT04188808RECRUITINGNA
View Study
130 participants
INTERVENTIONAL
Gothenburg, Sweden +1 more
Started: Sep 1, 2018

Efficacy and Safety of the Regulatory Polypeptides in Patients With Peripheral Atherosclerosis.

NCT05933720RECRUITINGNA
View Study
120 participants
INTERVENTIONAL
Ryazan, Russia
Started: Apr 1, 2023
Completed Clinical Trials
4 completed trials for Surgical Revascularization (Bypass Surgery) in Lower Extremity Peripheral Arterial Disease

IDOMENEO - Is Treatment Reality in Vascular Medicine Evidence-based and Follows Guideline Recommendations? A Project for Quality Development Exemplified by Peripheral Arterial Disease (PAD)

NCT03098290COMPLETED
View Study
5.61K participants
OBSERVATIONAL
Bad Berka, Germany +34 more
Started: May 1, 2018

Revascularization With Open Bypass Versus Angioplasty and STenting of the Lower Extremity Trial (ROBUST)

NCT01602159COMPLETEDNA
View Study
29 participants
INTERVENTIONAL
Baltimore, United States +1 more
Started: Jul 1, 2009

Medium-term Results of Lower Limb Arterial Bypass

NCT07093632COMPLETED
View Study
57 participants
OBSERVATIONAL
Lyon, France
Started: Jan 1, 2025

Registry of First-line Treatments in Patients With Critical Limb Ischemia

NCT01877252COMPLETED
View Study
1.2K participants
OBSERVATIONAL
Münster, Germany
Started: Jan 1, 2013