DFDA

Amoxicillin

Treatment for Lower Respiratory Infections

Typical Dosage: 500 mg - 1 g three times daily

Effectiveness
85%
Safety Score
70%
Clinical Trials
1
Participants
200K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
500 mg - 1 g three times daily
Time to Effect
1-2 days
Treatment Duration
5-7 days
Evidence Quality
HIGH
Number Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$15
Monitoring:$250
Side Effect Mgmt:$5
Total Annual:$270
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$15,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$317.65
Cost per Remission
$337.5
Comparison vs Azithromycin
Cost Difference
$-20/year
Less expensive
QALY Difference
0.00 QALYs
Same outcomes
Dominance
DOMINATESBetter + cheaper
Prescription Access Economics
Physician Visit Cost
$150/year
Time Cost
$30/year
Travel + wait time
Insurance Admin Cost
$20/year
Prior auth, claims
Rx Price
$15/year
Potential OTC Price
$10/year
Estimated if OTC available
Early Treatment Benefit
+0.05 QALYs
From faster OTC access
Risk Assessment
Misuse Risk
MODERATE
Missed Diagnosis Risk
LOW
Amoxicillin Outcomes

for Lower Respiratory Infections

Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+85%
Remission Rate
+80%
Common Side Effects
Diarrhea
+7%
Nausea/vomiting
+3%
Rash
+2%
Allergic reaction
+0.05%

Sources:

nih.gov
bjgp.org
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Amoxicillin in Lower Respiratory Infections

Multimodal Stewardship Programme to Improve Antibiotic Prescribing for Children With Lower Respiratory Tract Infections

NCT07893834NOT YET RECRUITINGNA
View Study
50K participants
INTERVENTIONAL
Helsinki, Finland
Started: Jan 1, 2027