DFDA

Azithromycin

Treatment for Lower Respiratory Infections

Typical Dosage: 500 mg Day 1, then 250 mg daily for 4 days

Effectiveness
85%
Safety Score
70%
Clinical Trials
6
Participants
150K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
500 mg Day 1, then 250 mg daily for 4 days
Time to Effect
1-2 days
Treatment Duration
3-5 days
Evidence Quality
HIGH
Number Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
20(Treat 20 patients to see 1 additional serious adverse event)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$250
Side Effect Mgmt:$5
Total Annual:$285
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$20,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$335.29
Cost per Remission
$356.25
Comparison vs Amoxicillin
Cost Difference
+$15/year
More expensive
QALY Difference
+0.00 QALYs
Better outcomes
Dominance
No dominance
Prescription Access Economics
Physician Visit Cost
$150/year
Time Cost
$30/year
Travel + wait time
Insurance Admin Cost
$20/year
Prior auth, claims
Rx Price
$30/year
Potential OTC Price
$17.5/year
Estimated if OTC available
Early Treatment Benefit
+0.05 QALYs
From faster OTC access
Risk Assessment
Misuse Risk
MODERATE
Missed Diagnosis Risk
LOW
Azithromycin Outcomes

for Lower Respiratory Infections

Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+85%
Remission Rate
+80%
Common Side Effects
Diarrhea
+6%
Nausea/vomiting
+5%
Abdominal pain
+4%
QT prolongation
+0.05%

Sources:

oup.com
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
3 completed trials for Azithromycin in Lower Respiratory Infections

Compliance And Safety Study In Children With Upper And Lower Respiratory Tract Infections

NCT00939185COMPLETED
View Study
400 participants
OBSERVATIONAL
Started: Apr 1, 2007

Bioequivalence Study of Azithromycin Capsule and Reference Formulation Sumamed * in Healthy Adult Subjects in China

NCT06149117COMPLETEDPHASE4
View Study
48 participants
INTERVENTIONAL
Beijing, China
Started: Nov 16, 2022

Anti-inflammatory Effects of Macrolide Treatment in Influenza Lower Respiratory Tract Infections

NCT01779570COMPLETEDPHASE4
View Study
68 participants
INTERVENTIONAL
Hong Kong, Hong Kong +1 more
Started: Feb 1, 2013