DFDA

Azathioprine

Treatment for Lupus

Typical Dosage: 1-3 mg/kg daily

Effectiveness
70%
Safety Score
35%
Clinical Trials
40
Participants
12K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
35
DangerousModerateSafe
Treatment Details
Dosage Range
1-3 mg/kg daily
Time to Effect
3-6 months
Treatment Duration
Lifetime for maintenance
Evidence Quality
MODERATE
Number Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$700
Side Effect Mgmt:$300
Total Annual:$1,200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$25,000/QALY
QALYs Gained
0.6
Outcome-Based Costs
Cost per Responder
$2,400
Cost per Remission
$4,800
Azathioprine Outcomes

for Lupus

Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+50%
Remission Rate
+25%
Common Side Effects
Nausea, vomiting
+15%
Leukopenia, thrombocytopenia
+15%
Increased infection risk
+20%
Hepatotoxicity (rare)
+3%

Sources:

oup.com
oup.com
oup.com

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Azathioprine in Lupus

SGLT2 Inhibitor in Lupus Nephritis Patients With Chronic Kidney Disease

NCT06155604RECRUITINGPHASE2
View Study
150 participants
INTERVENTIONAL
Hong Kong, Hong Kong
Started: Jan 4, 2023
Completed Clinical Trials
10 completed trials for Azathioprine in Lupus

Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis.

NCT00204022COMPLETEDPHASE3
View Study
105 participants
INTERVENTIONAL
Brussels, Belgium
Started: Feb 1, 2001

Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis

NCT02949349COMPLETEDPHASE2
View Study
32 participants
INTERVENTIONAL
Started: Jul 1, 2015

Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis

NCT02645565COMPLETEDPHASE4
View Study
75 participants
INTERVENTIONAL
Puducherry, India
Started: Dec 1, 2015

Abatacept and Cyclophosphamide Combination Therapy for Lupus Nephritis

NCT00774852COMPLETEDPHASE2
View Study
137 participants
INTERVENTIONAL
Birmingham, United States +22 more
Started: Nov 1, 2008

Long-Term Study of Multi-target Therapy as Maintenance Treatment for Lupus Nephritis

NCT01056237COMPLETEDNA
View Study
206 participants
INTERVENTIONAL
Nanjing, China
Started: Feb 1, 2010

A Study of Mycophenolate Mofetil (CellCept) in Management of Patients With Lupus Nephritis.

NCT00377637COMPLETEDPHASE3
View Study
370 participants
INTERVENTIONAL
Huntsville, United States +107 more
Started: Jul 1, 2005

Enteric-coated Mycophenolate Sodium Versus Azathioprine for the Extra-renal Lupus Manifestations

NCT01112215COMPLETEDPHASE4
View Study
240 participants
INTERVENTIONAL
Barcelona, Spain
Started: Dec 1, 2009

The Frequency of Thiopurine Methyltransferase Polymorphism in Systemic Lupus Erythematosus SLE

NCT07012239COMPLETED
View Study
348 participants
OBSERVATIONAL
Dhaka, Bangladesh
Started: Jan 1, 2016

Weaning of Immunosuppression in Nephritis of Lupus

NCT01284725COMPLETEDPHASE3
View Study
100 participants
INTERVENTIONAL
Marseille, France
Started: Feb 16, 2011

Prospective, Randomized, Multicenter, Control Study to Assess the Efficacy and Safety of Tacrolimus in Induction and Maintenance Phase Treatment in Lupus Nephritis

NCT00615173COMPLETEDPHASE3
View Study
81 participants
INTERVENTIONAL
Guangzhou, China
Started: Jul 1, 2006
Showing 20 of 40 total trials