Mycophenolate Mofetil
Treatment for Lupus
Typical Dosage: 1-3g daily
Effectiveness
80%
Safety Score
35%
Clinical Trials
81
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
35
DangerousModerateSafe
Treatment Details
Dosage Range
1-3g daily
Time to Effect
3-6 months
Treatment Duration
6-24 months induction, then maintenance (often lifetime)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$1,000
Monitoring:$800
Side Effect Mgmt:$400
Total Annual:$2,200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$45,000/QALY
QALYs Gained
0.7
Outcome-Based Costs
Cost per Responder
$3,667
Cost per Remission
$5,500
Active Clinical Trials
2 active trials recruiting for Mycophenolate Mofetil in Lupus
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
NCT05538208RECRUITINGPHASE2
105 participants
INTERVENTIONAL
San Francisco, United States +18 more
Started: Jun 7, 2024
Effectiveness of Mycophenolate Mofetil Combined With Tacrolimus for Steroid Tapering in Systemic Lupus Erythematosus
NCT05916781RECRUITINGPHASE4
220 participants
INTERVENTIONAL
Beijing, China
Started: Jul 1, 2023
Completed Clinical Trials
10 completed trials for Mycophenolate Mofetil in Lupus
Concentration-controlled Therapy of Mycophenolate Mofetil (MMF) in Proliferative Lupus Nephritis
NCT01042457COMPLETEDPHASE3
24 participants
INTERVENTIONAL
Bangkok, Thailand
Started: May 1, 2009
A Pharmacoeconomic Study Comparing the Use of Mycophenolate Mofetil or Cyclophosphamide as Induction Therapy in Lupus Nephritis Patients in Egypt
NCT05195086COMPLETED
122 participants
OBSERVATIONAL
Cairo, Egypt
Started: Jul 1, 2018
Comparing the Efficacy of Tacrolimus and Mycophenolate Mofetil for the Initial Therapy of Active Lupus Nephritis
NCT00371319COMPLETEDPHASE4
150 participants
INTERVENTIONAL
Hong Kong, China
Started: Sep 1, 2005
Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis.
NCT00204022COMPLETEDPHASE3
105 participants
INTERVENTIONAL
Brussels, Belgium
Started: Feb 1, 2001
Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis
NCT02630628COMPLETEDPHASE3
130 participants
INTERVENTIONAL
Hong Kong, Hong Kong
Started: Dec 5, 2015
Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis
NCT02949349COMPLETEDPHASE2
32 participants
INTERVENTIONAL
Started: Jul 1, 2015
Cyclophosphamide Versus Mycophenolate Mofetil in Lupus Nephritis
NCT03200002COMPLETEDPHASE2
49 participants
INTERVENTIONAL
Started: Jan 1, 2014
Mycophenolate Mofetil in Systemic Lupus Erythematosus (MISSILE)
NCT01101802COMPLETEDPHASE4
71 participants
INTERVENTIONAL
London, United Kingdom
Started: Mar 1, 2006
Biomarker-Linked Outcomes of Cellcept in Lupus Arthritis
NCT00594932COMPLETEDPHASE1, PHASE2
27 participants
INTERVENTIONAL
Oklahoma City, United States
Started: Nov 1, 2006
A Study of Mycophenolate Mofetil (CellCept) in Management of Patients With Lupus Nephritis.
NCT00377637COMPLETEDPHASE3
370 participants
INTERVENTIONAL
Huntsville, United States +107 more
Started: Jul 1, 2005
Showing 20 of 81 total trials