Intratympanic Dexamethasone
Treatment for Menieres Disease
Typical Dosage: 10-24 mg/mL, 0.3-0.5 mL per injection
Effectiveness
78%
Safety Score
70%
Clinical Trials
8
Participants
3.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
10-24 mg/mL, 0.3-0.5 mL per injection
Time to Effect
Days to 2 weeks
Treatment Duration
As needed, usually 1-3 injections per flare-up or series
Evidence Quality
MODERATENumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$450
Side Effect Mgmt:$50
Total Annual:$2,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.45
Outcome-Based Costs
Cost per Responder
$2,667
Cost per Remission
$4,000
Intratympanic Dexamethasone Outcomes
for Menieres Disease
Efficacy Outcomes
Overall Effectiveness
+78%
Response Rate
+75%
Remission Rate
+50%
Common Side Effects
Ear discomfort/pain
+15%
Transient vertigo
+7%
Ear infection
+3%
Tympanic membrane perforation
+1%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov