DFDA

Surgery (Pleurectomy/Decortication or Extrapleural Pneumonectomy) + Adjuvant Therapy

Treatment for Mesothelioma

Typical Dosage: N/A (surgical procedure)

Effectiveness
85%
Safety Score
25%
Clinical Trials
1
Participants
15K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
25
DangerousModerateSafe
Treatment Details
Dosage Range
N/A (surgical procedure)
Time to Effect
Immediate tumor removal, long recovery (weeks-months)
Treatment Duration
Single procedure, followed by long recovery and adjuvant therapy for months-years
Evidence Quality
MODERATE
Confidence Score
75%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$25,000
Side Effect Mgmt:$25,000
Total Annual:$150,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
POOR
ICER
$200,000/QALY
QALYs Gained
1
Outcome-Based Costs
Cost per Remission
$1,000,000
Comparison vs Multimodal therapy without surgery
Cost Difference
+$120,000/year
More expensive
QALY Difference
+0.50 QALYs
Better outcomes
Dominance
No dominance
Surgery (Pleurectomy/Decortication or Extrapleural Pneumonectomy) + Adjuvant Therapy Outcomes

for Mesothelioma

Efficacy Outcomes
Overall Effectiveness
+85%
Remission Rate
+15%
Common Side Effects
Post-operative pain
+70%
Respiratory complications (e.g., pneumonia)
+30%
Cardiac complications (e.g., arrhythmia)
+15%
Empyema/Infection
+10%
Hemorrhage
+7%
Mortality (EPP)
+8%
Mortality (P/D)
+3%

Sources:

nih.gov
mq.edu.au
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
1 completed trial for Surgery (Pleurectomy/Decortication or Extrapleural Pneumonectomy) + Adjuvant Therapy in Mesothelioma

Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma

NCT00354393COMPLETEDPHASE2
View Study
9 participants
INTERVENTIONAL
Cleveland, United States
Started: Aug 1, 2002