Sumatriptan
Treatment for Migraine
Typical Dosage: 25-100mg oral, 6mg subcutaneous
Effectiveness
78%
Safety Score
60%
Clinical Trials
103
Participants
200K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
25-100mg oral, 6mg subcutaneous
Time to Effect
30 minutes - 2 hours
Treatment Duration
As needed
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$150
Monitoring:$50
Side Effect Mgmt:$50
Total Annual:$250
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$8,000/QALY
QALYs Gained
0.05
Outcome-Based Costs
Cost per Responder
$357
Sumatriptan Outcomes
for Migraine
Efficacy Outcomes
Overall Effectiveness
+78%
Response Rate
+70%
Common Side Effects
Chest tightness/pressure
+5%
Tingling/numbness
+4%
Dizziness
+3%
Flushing
+2%
Sources:
Active Clinical Trials
1 active trial recruiting for Sumatriptan in Migraine
Migraine Attack Treatment Response Molecular and Clinical BiOmarkers (MAMBO) Phase I
NCT06503848RECRUITING
108 participants
OBSERVATIONAL
Barcelona, Spain
Started: Jan 25, 2024
Completed Clinical Trials
18 completed trials for Sumatriptan in Migraine
An Open-label, Randomized, 3-period Crossover Study to Evaluate Sumatriptan Pharmacokinetics for a TREXIMA™ (Sumatriptan Succinate / Naproxen Sodium) Tablet Followed by IMITREX® (Sumatriptan Succinate)
NCT00875784COMPLETEDPHASE1
30 participants
INTERVENTIONAL
Tacoma, United States
Started: May 6, 2008
Evaluation of Treatment Satisfaction and Preference for Sumavel DosePro in the Treatment of Migraine
NCT01016834COMPLETEDPHASE4
246 participants
INTERVENTIONAL
Birmingham, United States +20 more
Started: Nov 1, 2009
Comparison of Ketorolac Nasal Spray to Sumatriptan Nasal Spray and Placebo for Acute Treatment of Migraine
NCT01807234COMPLETEDPHASE4
72 participants
INTERVENTIONAL
Baltimore, United States
Started: Feb 1, 2013
Bioavailability Study to Compare OPTINOSE SUMATRIPTAN With IMITREX® in Healthy Subjects
NCT01507610COMPLETEDPHASE1
20 participants
INTERVENTIONAL
Neptune City, United States
Started: Jan 1, 2012
Study Of Sumatriptan Succinate Injection Kit In Patients With Migraine or Cluster Headache In Japan
NCT00356603COMPLETEDPHASE3
75 participants
INTERVENTIONAL
Aichi, Japan +3 more
Started: Jun 20, 2006
Drug Use Investigation for IMIGRAN Tablet
NCT01376141COMPLETED
3.57K participants
OBSERVATIONAL
Started: Sep 1, 2001
Sumatriptan and Naratriptan Pregnancy Registry
NCT01059604COMPLETED
868 participants
OBSERVATIONAL
Started: Dec 1, 2001
Sofusa System With Sumatriptan (KC5010) Phase 1 Dose Escalation Safety and PK Study (KCC-SMT-002)
NCT03229798COMPLETEDPHASE1
19 participants
INTERVENTIONAL
Raleigh, United States
Started: Jan 17, 2018
Effect of Sumatriptan on the Postoperative Quality of Recovery After Elective Minimally Invasive Craniotomy
NCT01632657COMPLETEDNA
40 participants
INTERVENTIONAL
Toronto, Canada
Started: Jun 1, 2012
Pretreatment With Sumatriptan on Cilostazol Induced Headache in Healthy Volunteers
NCT03156920COMPLETEDNA
30 participants
INTERVENTIONAL
Copenhagen, Denmark
Started: May 23, 2017
Influence of Ubrogepant and Sumatriptan on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin
NCT05654298COMPLETEDNA
20 participants
INTERVENTIONAL
Leuven, Belgium
Started: Mar 15, 2022
Study to Evaluate the Efficacy and Safety of Oral Sumatriptan for the Acute Treatment of Migraine in Children and Adolescents
NCT00963937COMPLETEDPHASE3
178 participants
INTERVENTIONAL
Aichi, Japan +15 more
Started: Sep 28, 2009
Comparison of Treximet & Imitrex as They Affect the Levels of Inflammatory Markers When the Patient is Actively Having a Migraine Headache
NCT01916395COMPLETED
30 participants
OBSERVATIONAL
Kalamazoo, United States
Started: Dec 1, 2009
The Effect of Sumatriptan and Placebo on Cilostazol Induced Headache
NCT02486276COMPLETEDNA
30 participants
INTERVENTIONAL
Copenhagen, Denmark
Started: Jun 1, 2015
Safety & Efficacy of a Single Dose of Sumatriptan Powder Delivered Intranasally With the Bi-directional Device in Adults With Acute Migraine
NCT01462812COMPLETEDPHASE3
223 participants
INTERVENTIONAL
San Francisco, United States +14 more
Started: Jan 1, 2011
Neuropeptides in the Humane Intra- og Extracerebral Circulation.
NCT00399633COMPLETEDNA
16 participants
INTERVENTIONAL
Glostrup, Copenhagen, Denmark
Started: Jan 1, 2007
Study to Evaluate the Safety, Tolerability, and Blood Pressure Effect of an Oral Dose of Sumatriptan Alone and in Combination With MK-0974 (Telcagepant) in Migraine Patients (0974-026)
NCT00701389COMPLETEDPHASE1
24 participants
INTERVENTIONAL
Started: Nov 20, 2007
Migraine Study in Adolescent Patients
NCT00843024COMPLETEDPHASE3
589 participants
INTERVENTIONAL
Gilbert, United States +78 more
Started: Dec 1, 2008
Showing 20 of 103 total trials