Posterior Fossa Decompression (for symptomatic Chiari II)
Treatment for Neural Tube Defects
Typical Dosage: N/A (surgical procedure)
Effectiveness
70%
Safety Score
55%
Clinical Trials
50
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
N/A (surgical procedure)
Time to Effect
Days to weeks
Treatment Duration
Single surgical intervention
Evidence Quality
MODERATENumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$750
Side Effect Mgmt:$3,000
Total Annual:$53,750
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEQALYs Gained
0.7
Outcome-Based Costs
Cost per Responder
$71,666.67
Posterior Fossa Decompression (for symptomatic Chiari II) Outcomes
for Neural Tube Defects
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+75%
Common Side Effects
CSF leak
+7%
Surgical site infection
+4%
Persistent symptoms
+25%
Meningitis
+2%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov