DFDA

5-Fluorouracil (topical)

Treatment for Non Melanoma Skin Cancer Squamous Cell Carcinoma

Typical Dosage: 5% cream, twice daily

Effectiveness
85%
Safety Score
60%
Clinical Trials
2
Participants
30K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
5% cream, twice daily
Time to Effect
2-4 weeks
Treatment Duration
2-4 weeks
Evidence Quality
HIGH
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100
Monitoring:$200
Side Effect Mgmt:$50
Total Annual:$350
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$20,000/QALY
QALYs Gained
0.7
Outcome-Based Costs
Cost per Responder
$412
Cost per Remission
$412
Comparison vs Surgical Excision
Cost Difference
$-1,500/year
Less expensive
QALY Difference
-0.05 QALYs
Worse outcomes
Dominance
No dominance
5-Fluorouracil (topical) Outcomes

for Non Melanoma Skin Cancer Squamous Cell Carcinoma

Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+85%
Remission Rate
+85%
Common Side Effects
Erythema (redness)
+95%
Crusting/erosion
+80%
Pain/burning/soreness
+80%
Edema (swelling)
+60%
Pruritus (itching)
+60%

Sources:

nih.gov
nih.gov
semanticscholar.org

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
1 completed trial for 5-Fluorouracil (topical) in Non Melanoma Skin Cancer Squamous Cell Carcinoma

CSP #562 - The VA Keratinocyte Carcinoma Chemoprevention Trial

NCT00847912COMPLETEDPHASE4
View Study
954 participants
INTERVENTIONAL
Palo Alto, United States +12 more
Started: Jun 26, 2009