Surgical Aortic Valve Replacement (SAVR)
Treatment for Non Rheumatic Calcific Aortic Valve Disease
Effectiveness
92%
Safety Score
40%
Clinical Trials
800
Participants
200K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
40
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate hemodynamic improvement, symptomatic relief within weeks to months post-recovery
Treatment Duration
One-time procedure; valve durability 10-20+ years; initial procedure cost $25,000-$50,000.
Evidence Quality
HIGHNumber Needed to Treat (NNT)
2(Treat 2 patients to see 1 additional successful outcome)
Confidence Score
98%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$1,500
Side Effect Mgmt:$1,200
Total Annual:$2,700
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$70,000/QALY
QALYs Gained
1.6
Comparison vs Transcatheter Aortic Valve Replacement (TAVR)
Cost Difference
$-5,000/year
Less expensive
QALY Difference
-0.10 QALYs
Worse outcomes
Dominance
No dominance
Surgical Aortic Valve Replacement (SAVR) Outcomes
for Non Rheumatic Calcific Aortic Valve Disease
Efficacy Outcomes
Overall Effectiveness
+92%
Response Rate
+92%
Remission Rate
+99%
Common Side Effects
Major bleeding
+15%
Stroke
+2%
Acute kidney injury
+10%
Atrial fibrillation
+20%
Sternal wound infection
+3%
Prolonged recovery
+30%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov