DFDA

Intra-articular Corticosteroid Injections (IACI)

Treatment for Osteoarthritis

Typical Dosage: Triamcinolone 20-40mg or Methylprednisolone 40-80mg per joint

Effectiveness
70%
Safety Score
60%
Clinical Trials
2
Participants
50K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
Triamcinolone 20-40mg or Methylprednisolone 40-80mg per joint
Time to Effect
1-2 days
Treatment Duration
Repeated every 3-4 months, limited to 3-4 per year
Evidence Quality
HIGH
Number Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$600
Monitoring:$1,200
Side Effect Mgmt:$50
Total Annual:$1,850
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$25,000/QALY
QALYs Gained
0.07
Outcome-Based Costs
Cost per Responder
$867
Comparison vs Oral NSAIDs
Cost Difference
+$275/year
More expensive
QALY Difference
+0.01 QALYs
Better outcomes
Dominance
No dominance
Intra-articular Corticosteroid Injections (IACI) Outcomes

for Osteoarthritis

Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+75%
Common Side Effects
Post-injection flare
+15%
Infection
+0.05%
Skin atrophy/depigmentation
+3%
Elevated blood glucose (in diabetics)
+7%

Sources:

nih.gov
bmj.com
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
2 active trials recruiting for Intra-articular Corticosteroid Injections (IACI) in Osteoarthritis

Intra-articular Corticosteroid Injection in GAE for Knee Knee Osteoarthritis

NCT06514716RECRUITINGNA
View Study
60 participants
INTERVENTIONAL
Zagazig, Egypt
Started: Sep 29, 2024

Corticosteroid Injection Versus Nerve Block

NCT06735027RECRUITINGNA
View Study
40 participants
INTERVENTIONAL
Minneapolis, United States
Started: Jan 2, 2025