Topical NSAIDs (e.g., Diclofenac gel)
Treatment for Osteoarthritis
Typical Dosage: Apply 2-4g to affected joint 3-4 times daily
Effectiveness
70%
Safety Score
80%
Clinical Trials
200
Participants
40K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
80
DangerousModerateSafe
Treatment Details
Dosage Range
Apply 2-4g to affected joint 3-4 times daily
Time to Effect
1-2 weeks
Treatment Duration
Ongoing as needed
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$150
Monitoring:$1,200
Side Effect Mgmt:$50
Total Annual:$1,400
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$15,000/QALY
QALYs Gained
0.06
Outcome-Based Costs
Cost per Responder
$308
Comparison vs Oral NSAIDs
Cost Difference
+$50/year
More expensive
QALY Difference
-0.02 QALYs
Worse outcomes
Dominance
No dominance
Prescription Access Economics
Annual Societal Loss per Patient
$530
Cost of prescription-only barriers (visits, time, admin, price premium)
Physician Visit Cost
$250/year
Time Cost
$140/year
Travel + wait time
Insurance Admin Cost
$40/year
Prior auth, claims
Rx Price
$150/year
Potential OTC Price
$50/year
Estimated if OTC available
Early Treatment Benefit
+0.10 QALYs
From faster OTC access
Risk Assessment
Misuse Risk
LOWMissed Diagnosis Risk
LOWActive Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov