Tympanostomy Tube Insertion
Treatment for Otitis Media
Effectiveness
90%
Safety Score
78%
Clinical Trials
60
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
78
DangerousModerateSafe
Treatment Details
Time to Effect
immediate (hearing), days/weeks (AOM reduction)
Treatment Duration
6-18 months (tube indwelling)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$300
Side Effect Mgmt:$100
Total Annual:$3,800
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$25,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$4,086
Cost per Remission
$4,318
Comparison vs Watchful Waiting
Cost Difference
+$3,745/year
More expensive
QALY Difference
+0.07 QALYs
Better outcomes
Dominance
No dominance
Tympanostomy Tube Insertion Outcomes
for Otitis Media
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+93%
Remission Rate
+88%
Common Side Effects
Otorrhea (ear discharge)
+15%
Tympanosclerosis
+40%
Premature tube extrusion
+8%
Persistent tympanic membrane perforation (rare)
+2%
Active Clinical Trials
5 active trials recruiting for Tympanostomy Tube Insertion in Otitis Media
Posterior Vs. Anterior Tympanostomy Tube Placement
NCT06191562ACTIVE NOT RECRUITINGNA
386 participants
INTERVENTIONAL
Pittsburgh, United States +1 more
Started: Feb 29, 2024
Clinical Study of the Solo+ Tympanostomy Tube Device
NCT04148417ACTIVE NOT RECRUITINGNA
27 participants
INTERVENTIONAL
Washington D.C., United States +1 more
Started: Feb 9, 2021
Post-Market Clinical Follow-Up Study of the Solo+ Tympanostomy Tube Device
NCT07029997NOT YET RECRUITING
160 participants
OBSERVATIONAL
Started: Jul 1, 2025
In-Office Clinical Study of the Solo+ TTD
NCT05741333RECRUITINGNA
66 participants
INTERVENTIONAL
Alexander City, United States +6 more
Started: Mar 30, 2023
Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry
NCT05915078RECRUITING
200 participants
OBSERVATIONAL
Louisville, United States +5 more
Started: Jun 15, 2023
Completed Clinical Trials
11 completed trials for Tympanostomy Tube Insertion in Otitis Media
Evaluation of the Tympanostomy Tube Delivery System
NCT01202578COMPLETEDPHASE2, PHASE3
53 participants
INTERVENTIONAL
Port Saint Lucie, United States +3 more
Started: Sep 1, 2010
Singapore Tympanostomy Tube Delivery System Study
NCT01046877COMPLETEDNA
25 participants
INTERVENTIONAL
Singapore, Singapore
Started: Dec 1, 2008
Adenoidectomy, Myringotomy and Tubes' Insertion vs Adenoidectomy and Myringotomy Alone in Children With Otitis Media With Effusion and Adenoid Hypertrophy
NCT00629694COMPLETEDPHASE2
52 participants
INTERVENTIONAL
Athens, Greece
Started: Sep 1, 2007
Study of the Hummingbird TTS™ Tympanostomy Tube System
NCT03503591COMPLETED
109 participants
OBSERVATIONAL
Minneapolis, United States +3 more
Started: Jan 29, 2016
Short-term Effects of Ventilation Tubes in Children With Chronic Otitis Media With Effusion
NCT06100159COMPLETEDNA
60 participants
INTERVENTIONAL
Fredericia, Denmark +1 more
Started: Jan 20, 2017
Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11
NCT00365092COMPLETEDNA
400 participants
INTERVENTIONAL
Pittsburgh, United States
Started: Apr 1, 2002
Acclarent Tympanostomy Tube Delivery System for the Treatment of Patients Requiring Tympanostomy Tube Insertion
NCT02150044COMPLETEDNA
29 participants
INTERVENTIONAL
Kirkland, United States
Started: Feb 1, 2010
In-Office Tympanostomy Tube Placement in Children (OTTER)
NCT03323736COMPLETEDPHASE3
370 participants
INTERVENTIONAL
Carlsbad, United States +18 more
Started: Oct 31, 2017
inVENT-visIOn Study
NCT01444391COMPLETEDNA
42 participants
INTERVENTIONAL
Port Saint Lucie, United States
Started: Oct 1, 2011
Hummingbird TTS Ear Tube Delivery Study
NCT02165384COMPLETEDNA
199 participants
INTERVENTIONAL
Maple Grove, United States +3 more
Started: Jan 1, 2014
inVENT-In-Office Study
NCT01324271COMPLETEDNA
85 participants
INTERVENTIONAL
San Antonio, United States
Started: Jan 1, 2011
Showing 20 of 60 total trials