DFDA

Co-trimoxazole (Trimethoprim-sulfamethoxazole)

Treatment for Paratyphoid Fever

Typical Dosage: 160 mg Trimethoprim/800 mg Sulfamethoxazole twice daily

Effectiveness
75%
Safety Score
70%
Clinical Trials
25
Participants
5K

Comparative Safety Scale(Higher is safer)

Cyanide☠ī¸
Meth💀
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Morphine💊
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Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
160 mg Trimethoprim/800 mg Sulfamethoxazole twice daily
Time to Effect
3-5 days
Treatment Duration
10-14 days
Evidence Quality
MODERATE
Confidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$15
Monitoring:$400
Side Effect Mgmt:$10
Total Annual:$425
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATE
Outcome-Based Costs
Cost per Responder
$544.87
Cost per Remission
$566.67
Prescription Access Economics
Physician Visit Cost
$150/year
Time Cost
$50/year
Travel + wait time
Insurance Admin Cost
$15/year
Prior auth, claims
Rx Price
$15/year
Potential OTC Price
$8/year
Estimated if OTC available
Risk Assessment
Misuse Risk
MODERATE
Missed Diagnosis Risk
HIGH
Co-trimoxazole (Trimethoprim-sulfamethoxazole) Outcomes

for Paratyphoid Fever

Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+78%
Remission Rate
+75%
Common Side Effects
Nausea
+5%
Vomiting
+4%
Rash
+3%

Sources:

nih.gov
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov