Dopamine Agonists (e.g., Pramipexole, Ropinirole)
Treatment for Parkinson S Disease
Typical Dosage: Pramipexole 0.125-1.5 mg TID; Ropinirole 0.25-24 mg TID
Effectiveness
82%
Safety Score
60%
Clinical Trials
300
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
Pramipexole 0.125-1.5 mg TID; Ropinirole 0.25-24 mg TID
Time to Effect
1-4 weeks
Treatment Duration
Lifetime
Evidence Quality
HIGHConfidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$500
Monitoring:$900
Side Effect Mgmt:$900
Total Annual:$2,300
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$60,000/QALY
QALYs Gained
0.8
Outcome-Based Costs
Cost per Responder
$3,066.67
Comparison vs Levodopa
Cost Difference
+$200/year
More expensive
QALY Difference
-0.10 QALYs
Worse outcomes
Dominance
No dominance
Dopamine Agonists (e.g., Pramipexole, Ropinirole) Outcomes
for Parkinson S Disease
Efficacy Outcomes
Overall Effectiveness
+82%
Response Rate
+75%
Common Side Effects
Nausea
+30%
Somnolence/Sudden sleep attacks
+20%
Impulse Control Disorders
+10%
Hallucinations
+15%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov