Sucralfate
Treatment for Peptic Ulcer Disease
Typical Dosage: 1g four times daily
Effectiveness
60%
Safety Score
85%
Clinical Trials
100
Participants
20K
Comparative Safety Scale(Higher is safer)
Cyanideâ ī¸
Methđ
CigarettesđŦ
Chemoâĸī¸
Alcoholđē
Morphineđ
Antibioticsđ
Tylenolđ
Exerciseđ
Waterđ§
85
DangerousModerateSafe
Treatment Details
Dosage Range
1g four times daily
Time to Effect
Weeks for healing
Treatment Duration
4-8 weeks
Evidence Quality
MODERATENumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
50(Treat 50 patients to see 1 additional serious adverse event)
Confidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$150
Monitoring:$50
Side Effect Mgmt:$20
Total Annual:$220
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$25,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$366.67
Cost per Remission
$440
Prescription Access Economics
Annual Societal Loss per Patient
$370
Cost of prescription-only barriers (visits, time, admin, price premium)
Physician Visit Cost
$150/year
Time Cost
$50/year
Travel + wait time
Insurance Admin Cost
$20/year
Prior auth, claims
Rx Price
$150/year
Potential OTC Price
$75/year
Estimated if OTC available
Risk Assessment
Misuse Risk
LOWMissed Diagnosis Risk
LOWSucralfate Outcomes
for Peptic Ulcer Disease
Efficacy Outcomes
Overall Effectiveness
+60%
Response Rate
+60%
Remission Rate
+50%
Common Side Effects
Constipation
+7%
Dry mouth
+1%
Sources:
Active Clinical Trials
1 active trial recruiting for Sucralfate in Peptic Ulcer Disease
Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing
NCT07312370NOT YET RECRUITINGPHASE4
120 participants
INTERVENTIONAL
Lanzhou, China
Started: Apr 20, 2026