Gabapentin
Treatment for Peripheral Neuropathy
Typical Dosage: 900-3600 mg daily in 3 divided doses
Effectiveness
75%
Safety Score
62%
Clinical Trials
72
Participants
30K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
62
DangerousModerateSafe
Treatment Details
Dosage Range
900-3600 mg daily in 3 divided doses
Time to Effect
1-2 weeks
Treatment Duration
lifetime
Evidence Quality
MODERATENumber Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
8(Treat 8 patients to see 1 additional serious adverse event)
Confidence Score
83%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$180
Monitoring:$250
Side Effect Mgmt:$100
Total Annual:$530
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$15,000/QALY
QALYs Gained
0.06
Outcome-Based Costs
Cost per Responder
$1,104.17
Cost per Remission
$7,571.43
Comparison vs Pregabalin
Cost Difference
$-220/year
Less expensive
QALY Difference
-0.01 QALYs
Worse outcomes
Dominance
No dominance
Gabapentin Outcomes
for Peripheral Neuropathy
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+48%
Remission Rate
+7%
Common Side Effects
Dizziness
+20%
Somnolence
+20%
Peripheral edema
+7%
Fatigue
+5%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
15 completed trials for Gabapentin in Peripheral Neuropathy
A Study on the Efficacy and Safety of Gabapentin in the Treatment of Patients With Painful Diabetic Neuropathy
NCT00644748COMPLETEDPHASE4
95 participants
INTERVENTIONAL
Fortaleza, Brazil +9 more
Started: May 1, 2003
A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN)
NCT00643760COMPLETEDPHASE2
421 participants
INTERVENTIONAL
Alabaster, United States +89 more
Started: Mar 1, 2008
Botulinum Toxin Type A in Diabetic Peripheral Neuropathy
NCT05296759COMPLETEDPHASE4
30 participants
INTERVENTIONAL
Alexandria, Egypt
Started: Feb 1, 2021
Safety and Efficacy of Gabapentin in Diabetic Peripheral Neuropathy
NCT00712439COMPLETEDPHASE2
147 participants
INTERVENTIONAL
Started: Apr 1, 2006
Neuropathic Pain Management
NCT01263132COMPLETEDPHASE3
104 participants
INTERVENTIONAL
Pachuca, Mexico
Started: Feb 1, 2008
Trazodone/Gabapentin Fixed Dose Combination Products in Painful Diabetic Neuropathy
NCT03749642COMPLETEDPHASE2
240 participants
INTERVENTIONAL
Litomyšl, 570 01, Czechia +29 more
Started: Nov 22, 2018
A Study to Compare Safety and Efficacy of Tramadol Hydrochloride/Acetaminophen With Gabapentin in Participants With Diabetic Neuropathy
NCT00634543COMPLETEDPHASE4
162 participants
INTERVENTIONAL
Started: Dec 1, 2006
An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain
NCT00385671COMPLETEDPHASE4
407 participants
INTERVENTIONAL
Torrance, United States +8 more
Started: Sep 1, 2006
Therapeutic Interventions For Pain Induced By Vincristine Treatment For Childhood Acute Lymphoblastic Leukemia (ALL)
NCT01506453COMPLETEDPHASE2
51 participants
INTERVENTIONAL
Memphis, United States
Started: Jan 24, 2012
Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy
NCT00027963COMPLETEDPHASE3
100 participants
INTERVENTIONAL
Scottsdale, United States +22 more
Started: Feb 1, 2002
Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management
NCT01364298COMPLETEDPHASE4
353 participants
INTERVENTIONAL
Mexico City, Mexico
Started: Apr 1, 2011
A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions
NCT00904202COMPLETEDPHASE4
62 participants
INTERVENTIONAL
Birmingham, United States +6 more
Started: Jan 1, 2003
Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Induced Peripheral Neuropathy in Cancer Patients
NCT05510856COMPLETEDPHASE4
93 participants
INTERVENTIONAL
Tanta, Egypt
Started: Sep 1, 2022
Preoperative Gabapentine for Carpal Tunnel
NCT01632215COMPLETEDPHASE3
40 participants
INTERVENTIONAL
Started: Mar 1, 2010
A Controlled Clinical Trial Assessing the Efficacy of Vitamin B Prophylaxis in Attenuating Paclitaxel-induced Neuropathy and the Imperative Use of Gabapentin in Diabetic Ovarian Cancer Patients and the Potential Effect on Disease Response.
NCT07191587COMPLETEDNA
146 participants
INTERVENTIONAL
Cairo, Egypt
Started: Dec 1, 2024
Showing 20 of 72 total trials