DFDA

Topical Capsaicin (8% patch)

Treatment for Peripheral Neuropathy

Typical Dosage: One 8% patch applied for 60 minutes

Effectiveness
65%
Safety Score
80%
Clinical Trials
8
Participants
8K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
80
DangerousModerateSafe
Treatment Details
Dosage Range
One 8% patch applied for 60 minutes
Time to Effect
1-2 weeks
Treatment Duration
Applied every 3 months
Evidence Quality
MODERATE
Number Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$3,600
Monitoring:$1,200
Side Effect Mgmt:$50
Total Annual:$4,850
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$40,000/QALY
QALYs Gained
0.03
Outcome-Based Costs
Cost per Responder
$10,777.78
Cost per Remission
$161,666.67
Prescription Access Economics
Time Cost
$200/year
Travel + wait time
Risk Assessment
Misuse Risk
LOW
Missed Diagnosis Risk
LOW
Requires Monitoring
Yes
Needs lab work/checkups
Topical Capsaicin (8% patch) Outcomes

for Peripheral Neuropathy

Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+45%
Remission Rate
+3%
Common Side Effects
Application site pain
+70%
Application site erythema
+60%
Burning sensation
+50%

Sources:

ovid.com
metajournal.com
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
3 completed trials for Topical Capsaicin (8% patch) in Peripheral Neuropathy

Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch

NCT01416116COMPLETEDPHASE4
View Study
122 participants
INTERVENTIONAL
Antwerp, Belgium +19 more
Started: Jul 6, 2011

Study of NGX-4010 With the Use of Open Label Lidocaine (2.5%)/Prilocaine (2.5%) Cream for the Treatment of Postherpetic Neuralgia (PHN)

NCT00916942COMPLETEDPHASE2
View Study
20 participants
INTERVENTIONAL
Naples, United States +5 more
Started: Jun 1, 2009

A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical Capsaicin

NCT03587220COMPLETEDNA
View Study
44 participants
INTERVENTIONAL
Aalborg, Denmark
Started: Aug 1, 2018