DFDA

Combined Oral Contraceptives (COCs)

Treatment for Polycystic Ovary Syndrome

Typical Dosage: standard low-dose combined pill daily

Effectiveness
80%
Safety Score
60%
Clinical Trials
1
Participants
5M

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
standard low-dose combined pill daily
Time to Effect
1-3 months
Treatment Duration
long-term
Evidence Quality
HIGH
Number Needed to Treat (NNT)
2(Treat 2 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
10000(Treat 10000 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$75
Side Effect Mgmt:$50
Total Annual:$325
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$382
Combined Oral Contraceptives (COCs) Outcomes

for Polycystic Ovary Syndrome

Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+85%
Common Side Effects
Nausea
+15%
Breast tenderness
+10%
Headache
+8%
Mood changes
+7%
Venous Thromboembolism (VTE)
+0.01%

Sources:

nih.gov
nih.gov
researchgate.net

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
1 completed trial for Combined Oral Contraceptives (COCs) in Polycystic Ovary Syndrome

Effect of EE/NETA With Scaling on Periodontium and hsCRP in PCOS Women With Gingivitis

NCT05129878COMPLETEDNA
View Study
79 participants
INTERVENTIONAL
Rohtak, India +1 more
Started: Jan 1, 2022