Fluoxetine (SSRI)
Treatment for Premenstrual Syndrome
Typical Dosage: 10-20mg daily
Effectiveness
80%
Safety Score
60%
Clinical Trials
50
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
10-20mg daily
Time to Effect
1-2 weeks
Treatment Duration
Continuous or luteal phase
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
10(Treat 10 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$75
Monitoring:$100
Side Effect Mgmt:$50
Total Annual:$225
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$45,000/QALY
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$321
Cost per Remission
$563
Comparison vs Placebo
Cost Difference
+$225/year
More expensive
QALY Difference
+0.10 QALYs
Better outcomes
Dominance
No dominance
Fluoxetine (SSRI) Outcomes
for Premenstrual Syndrome
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+70%
Remission Rate
+40%
Common Side Effects
Nausea
+20%
Insomnia
+15%
Sexual dysfunction
+30%
Headache
+10%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov