NSAIDs (Ibuprofen/Naproxen)
Treatment for Premenstrual Syndrome
Typical Dosage: Ibuprofen 200-400mg every 4-6h / Naproxen 220-440mg every 8-12h
Effectiveness
50%
Safety Score
75%
Clinical Trials
2
Participants
15K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
Ibuprofen 200-400mg every 4-6h / Naproxen 220-440mg every 8-12h
Time to Effect
30-60 minutes
Treatment Duration
As needed (luteal phase)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
50(Treat 50 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$20
Monitoring:$600
Side Effect Mgmt:$10
Total Annual:$630
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$500/QALY
QALYs Gained
0.02
Outcome-Based Costs
Cost per Responder
$43
Cost per Remission
$300
NSAIDs (Ibuprofen/Naproxen) Outcomes
for Premenstrual Syndrome
Efficacy Outcomes
Overall Effectiveness
+50%
Response Rate
+70%
Remission Rate
+10%
Common Side Effects
Stomach upset
+10%
Heartburn
+8%
Headache
+5%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov