Oral Iron Supplementation (effective if iron deficient)
Treatment for Restless Legs Syndrome
Typical Dosage: Ferrous sulfate 325 mg daily or every other day (with Vitamin C)
Effectiveness
90%
Safety Score
85%
Clinical Trials
30
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
85
DangerousModerateSafe
Treatment Details
Dosage Range
Ferrous sulfate 325 mg daily or every other day (with Vitamin C)
Time to Effect
4-12 weeks
Treatment Duration
3-6 months then maintenance
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$90
Monitoring:$400
Side Effect Mgmt:$20
Total Annual:$510
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$1,000/QALY
QALYs Gained
0.4
Outcome-Based Costs
Cost per Responder
$638
Cost per Remission
$1,020
Oral Iron Supplementation (effective if iron deficient) Outcomes
for Restless Legs Syndrome
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+80%
Remission Rate
+50%
Common Side Effects
Constipation
+20%
Nausea
+10%
Abdominal pain
+8%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov