Enucleation
Treatment for Retinoblastoma
Typical Dosage: Not applicable
Effectiveness
100%
Safety Score
70%
Clinical Trials
10
Participants
0
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
Not applicable
Time to Effect
immediate
Treatment Duration
single surgery
Evidence Quality
HIGHConfidence Score
98%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$1,000
Monitoring:$15,000
Side Effect Mgmt:$1,500
Total Annual:$17,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
20.5
Outcome-Based Costs
Cost per Responder
$17,500
Cost per Remission
$17,500
Comparison vs Systemic Chemotherapy
Cost Difference
$-57,500/year
Less expensive
QALY Difference
-0.20 QALYs
Worse outcomes
Dominance
No dominance
Enucleation Outcomes
for Retinoblastoma
Efficacy Outcomes
Overall Effectiveness
+100%
Response Rate
+100%
Remission Rate
+100%
Common Side Effects
Post-operative pain
+90%
Swelling/Bruising
+80%
Phantom eye syndrome
+20%
Implant extrusion/migration
+10%
Infection
+5%
Sources:
Active Clinical Trials
5 active trials recruiting for Enucleation in Retinoblastoma
Adjuvant Chemotherapy for High-risk Retinoblastoma After Enucleation
NCT01906814ACTIVE NOT RECRUITINGPHASE3
179 participants
INTERVENTIONAL
Guangzhou, China
Started: Aug 1, 2013
Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009)
NCT02870907ACTIVE NOT RECRUITINGPHASE2
195 participants
INTERVENTIONAL
Saint-Denis, France +26 more
Started: Mar 18, 2010
Adjuvant Chemotherapy for High-risk Postenucleation Retinoblastoma
NCT05080010RECRUITINGPHASE3
500 participants
INTERVENTIONAL
Guangzhou, China
Started: Nov 1, 2020
Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma
NCT01783535ACTIVE NOT RECRUITINGPHASE2
174 participants
INTERVENTIONAL
Memphis, United States
Started: Jun 19, 2013
Effect of Treatment Modality on Psychosocial Functioning of Survivors of Unilateral Retinoblastoma
NCT03662776ENROLLING BY INVITATION
120 participants
OBSERVATIONAL
New York, United States +1 more
Started: Aug 31, 2018
Completed Clinical Trials
3 completed trials for Enucleation in Retinoblastoma
Superselective Intra-arterial Chemotherapy Treatment for Retinoblastoma- 5 Year Results From Turkey
NCT03935074COMPLETED
30 participants
OBSERVATIONAL
Istanbul, Turkey (Türkiye)
Started: Aug 30, 2016
Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma
NCT00186888COMPLETEDPHASE3
107 participants
INTERVENTIONAL
Memphis, United States
Started: Apr 7, 2005
Treatment Protocol for Non-Metastatic Unilateral Retinoblastoma
NCT03475121COMPLETEDPHASE3
84 participants
INTERVENTIONAL
Buenos Aires, Argentina
Started: Jan 1, 2018