DFDA

Ivermectin (topical)

Treatment for Rosacea

Typical Dosage: Apply thinly once daily to affected areas

Effectiveness
88%
Safety Score
88%
Clinical Trials
6
Participants
5K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
88
DangerousModerateSafe
Treatment Details
Dosage Range
Apply thinly once daily to affected areas
Time to Effect
2-4 weeks
Treatment Duration
12 weeks initial, then as needed or maintenance
Evidence Quality
HIGH
Number Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$2,500
Monitoring:$300
Side Effect Mgmt:$50
Total Annual:$2,850
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$26,000/QALY
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$3,800
Cost per Remission
$6,333
Comparison vs Topical Metronidazole
Cost Difference
+$2,000/year
More expensive
QALY Difference
+0.03 QALYs
Better outcomes
Dominance
No dominance
Prescription Access Economics
Annual Societal Loss per Patient
$2,000
Cost of prescription-only barriers (visits, time, admin, price premium)
Physician Visit Cost
$300/year
Time Cost
$120/year
Travel + wait time
Insurance Admin Cost
$80/year
Prior auth, claims
Rx Price
$2,500/year
Potential OTC Price
$800/year
Estimated if OTC available
Risk Assessment
Misuse Risk
LOW
Missed Diagnosis Risk
LOW
Ivermectin (topical) Outcomes

for Rosacea

Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+75%
Remission Rate
+45%
Common Side Effects
Skin irritation/burning/itching
+5%
Dry skin
+1%

Sources:

nih.gov
uu.nl
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Ivermectin (topical) in Rosacea

Analysis of the Microbiome in Rosacea

NCT04108897ACTIVE NOT RECRUITINGEARLY_PHASE1
View Study
150 participants
INTERVENTIONAL
Baltimore, United States
Started: Sep 17, 2019
Completed Clinical Trials
4 completed trials for Ivermectin (topical) in Rosacea

Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation.

NCT02806414COMPLETEDPHASE1, PHASE2
View Study
25 participants
INTERVENTIONAL
San Diego, United States
Started: Jul 1, 2016

MirvasO Soolantra Association In the Treatment of Moderate to Severe rosaCea.

NCT02616250COMPLETEDPHASE4
View Study
190 participants
INTERVENTIONAL
Fort Smith, United States +12 more
Started: Dec 1, 2015

Oracea Soolantra Association in Participants With Severe Rosacea

NCT03075891COMPLETEDPHASE4
View Study
273 participants
INTERVENTIONAL
Fort Smith, United States +20 more
Started: Jul 5, 2017

Evaluation of the Efficacy and Tolerance of Two Cosmetic Products in Subjects With Rosacea

NCT06582043COMPLETEDNA
View Study
70 participants
INTERVENTIONAL
Ciudad Autónoma de Buenos Aire, Argentina +1 more
Started: May 16, 2024