Oxamniquine
Treatment for Schistosomiasis
Typical Dosage: 15-20 mg/kg body weight, single oral dose
Effectiveness
90%
Safety Score
68%
Clinical Trials
100
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
68
DangerousModerateSafe
Treatment Details
Dosage Range
15-20 mg/kg body weight, single oral dose
Time to Effect
Rapid, days to weeks for symptom improvement
Treatment Duration
Single dose
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
100(Treat 100 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$10
Monitoring:$40
Side Effect Mgmt:$20
Total Annual:$70
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$600/QALY
QALYs Gained
0.9
Outcome-Based Costs
Cost per Responder
$73.68
Cost per Remission
$87.5
Comparison vs Praziquantel
Cost Difference
+$15/year
More expensive
QALY Difference
-0.10 QALYs
Worse outcomes
Dominance
No dominance
Oxamniquine Outcomes
for Schistosomiasis
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+95%
Remission Rate
+80%
Common Side Effects
Dizziness
+30%
Nausea
+15%
Headache
+10%
Abdominal pain
+8%
Convulsions (rare)
+0.5%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov