Gabapentin
Treatment for Shingles
Typical Dosage: 300-3600 mg daily in divided doses
Effectiveness
70%
Safety Score
65%
Clinical Trials
8
Participants
8K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
300-3600 mg daily in divided doses
Time to Effect
Days to weeks for full effect
Treatment Duration
Weeks to months
Evidence Quality
MODERATENumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
20(Treat 20 patients to see 1 additional serious adverse event)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$80
Monitoring:$150
Side Effect Mgmt:$50
Total Annual:$280
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$30,000/QALY
QALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$509.09
Gabapentin Outcomes
for Shingles
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+55%
Common Side Effects
Dizziness
+25%
Somnolence
+22%
Peripheral edema
+8%
Ataxia
+7%
Active Clinical Trials
1 active trial recruiting for Gabapentin in Shingles
Multimodal Nerve Block and Pulse Radiofrequency for Acute Herpes Zoster Pain
NCT06798662NOT YET RECRUITINGNA
120 participants
INTERVENTIONAL
Baotou, China
Started: Feb 1, 2025
Completed Clinical Trials
5 completed trials for Gabapentin in Shingles
Acupuncture in Herpes Zoster Neuralgia (ACUZoster)
NCT00885586COMPLETEDPHASE4
68 participants
INTERVENTIONAL
Munich, Germany
Started: Nov 1, 2008
Reduction of Postherpetic Neuralgia in Herpes Zoster
NCT01250561COMPLETEDNA
133 participants
INTERVENTIONAL
Houston, United States
Started: Feb 1, 2002
Safety and Efficacy of Gabapentin in Postherpetic Neuralgia
NCT00636636COMPLETEDPHASE3
452 participants
INTERVENTIONAL
Birmingham, United States +38 more
Started: Mar 1, 2008
Phase IV Study of FDA Approved, Once-Daily GRALISE™(Gabapentin) Tablets for the Treatment of Postherpetic Neuralgia
NCT01426230COMPLETED
201 participants
OBSERVATIONAL
Mobile, United States +36 more
Started: Sep 1, 2011
Ultrasound-Guided Erectro Spinae Plane Block Versus Stellate Ganglion Block for Patients With Upper Limb Acute Herpes Zoster Pain.
NCT06307444COMPLETEDNA
93 participants
INTERVENTIONAL
Tanta, Egypt
Started: Mar 20, 2024