DFDA

Pregabalin

Treatment for Shingles

Typical Dosage: 75-300 mg twice daily

Effectiveness
70%
Safety Score
65%
Clinical Trials
7
Participants
7K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
MethπŸ’€
Cigarettes🚬
Chemo☒️
Alcohol🍺
MorphineπŸ’Š
AntibioticsπŸ’‰
TylenolπŸ’Š
ExerciseπŸƒ
WaterπŸ’§
65
DangerousModerateSafe
Treatment Details
Dosage Range
75-300 mg twice daily
Time to Effect
Days to weeks for full effect
Treatment Duration
Weeks to months
Evidence Quality
MODERATE
Number Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
20(Treat 20 patients to see 1 additional serious adverse event)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$150
Monitoring:$150
Side Effect Mgmt:$50
Total Annual:$350
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$35,000/QALY
QALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$636.36
Pregabalin Outcomes

for Shingles

Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+55%
Common Side Effects
Dizziness
+30%
Somnolence
+25%
Peripheral edema
+8%
Weight gain
+7%

Sources:

nih.gov
bmj.com
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
2 active trials recruiting for Pregabalin in Shingles

Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic Neuralgia

NCT06969417RECRUITINGNA
View Study
50 participants
INTERVENTIONAL
Kharan, Pakistan
Started: Apr 10, 2025

Clinical Efficacy and Safety of Tender Point Infiltration (TPI) for Acute and Subacute Zoster Associated Pain

NCT06344403ACTIVE NOT RECRUITINGNA
View Study
136 participants
INTERVENTIONAL
Beijing, China
Started: Jun 1, 2025
Completed Clinical Trials
4 completed trials for Pregabalin in Shingles

Efficacy of Pregabalin for the Treatment of Acute Herpetic Neuralgia

NCT03809702COMPLETEDPHASE4
View Study
82 participants
INTERVENTIONAL
Dharān, Nepal
Started: Jul 15, 2018

Efficacy and Safety of Fire Needle Therapy Combined With Cortex Phellodendri Compound Fluid Wet Compress for Acute Herpes Zoster: a Randomized Controlled Trial.

NCT06985589COMPLETEDPHASE4
View Study
32 participants
INTERVENTIONAL
Xi'an, China
Started: Jan 1, 2024

Stellate Ganglion Block in Herpes Zoster

NCT04188327COMPLETEDNA
View Study
208 participants
INTERVENTIONAL
Tanta, Egypt +2 more
Started: May 1, 2020

Erector Spinae Plane Block in Post-herpetic Neuralgia

NCT04546334COMPLETEDNA
View Study
90 participants
INTERVENTIONAL
Tanta, Egypt
Started: Sep 26, 2020