Weight Loss (Lifestyle Modification)
Treatment for Sleep Apnea
Typical Dosage: Sustained caloric deficit, regular exercise
Effectiveness
85%
Safety Score
95%
Clinical Trials
18
Participants
100K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
Sustained caloric deficit, regular exercise
Time to Effect
6-12 months
Treatment Duration
Lifetime
Evidence Quality
HIGHConfidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$100
Side Effect Mgmt:$0
Total Annual:$250
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$10,000/QALY
QALYs Gained
1.5
Outcome-Based Costs
Cost per Responder
$357
Cost per Remission
$625
Weight Loss (Lifestyle Modification) Outcomes
for Sleep Apnea
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+70%
Remission Rate
+40%
Sources:
Active Clinical Trials
5 active trials recruiting for Weight Loss (Lifestyle Modification) in Sleep Apnea
Lifestyle Intervention for Obstructive Sleep Apnea in Women
NCT06370806NOT YET RECRUITINGNA
180 participants
INTERVENTIONAL
Started: May 1, 2024
Effect of Weight Loss From ESG Plus Lifestyle Changes vs. Lifestyle Changes Alone in Sleep Apnea Patients
NCT07082608RECRUITINGNA
74 participants
INTERVENTIONAL
Hyderabad, India
Started: Aug 19, 2025
Metabolism and Sleep Apnea Treatment
NCT05539716RECRUITINGNA
100 participants
INTERVENTIONAL
Miami, United States
Started: May 20, 2022
An Interactive Mobile Care on Self-management Among T2DM with OSA
NCT06760715NOT YET RECRUITINGNA
162 participants
INTERVENTIONAL
Miaoli, Taiwan
Started: Dec 30, 2024
Biological Sample Repository for Gastrointestinal Disorders
NCT05874726ACTIVE NOT RECRUITING
500 participants
OBSERVATIONAL
Boston, United States
Started: Jul 19, 2023
Completed Clinical Trials
12 completed trials for Weight Loss (Lifestyle Modification) in Sleep Apnea
Lifestyle Modification Using an App in OSA
NCT03189940COMPLETEDNA
59 participants
INTERVENTIONAL
Started: Jun 20, 2016
Obstructive Sleep Apnea in Obese Children and Teenagers - Occurrence and Importance of Intervention
NCT02463201COMPLETED
236 participants
OBSERVATIONAL
Holbæk, Denmark +1 more
Started: Apr 1, 2015
Effect of Weight Loss and CPAP on OSA and Metabolic Profile Stratified by Craniofacial Phenotype
NCT03287973COMPLETEDNA
194 participants
INTERVENTIONAL
Hong Kong, Hong Kong
Started: Sep 15, 2017
Life-style Changes in Obstructive Sleep Apnea
NCT01102920COMPLETEDNA
86 participants
INTERVENTIONAL
Uppsala, Sweden
Started: May 1, 2010
Lifestyle Intervention in Obstructive Sleep Apnoea
NCT01546792COMPLETEDPHASE2, PHASE3
60 participants
INTERVENTIONAL
Sheffield, United Kingdom +1 more
Started: Jan 1, 2010
Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach
NCT05104450COMPLETEDNA
696 participants
INTERVENTIONAL
Seattle, United States
Started: Apr 4, 2022
Lifestyle Intervention for OSA in Adults
NCT03851653COMPLETEDNA
89 participants
INTERVENTIONAL
Granada, Spain
Started: Apr 1, 2019
The Effectiveness of Smartphone Application on the Serevity of Obstructive Sleep Apnea
NCT05127239COMPLETEDNA
146 participants
INTERVENTIONAL
Miaoli, Taiwan
Started: Oct 15, 2020
Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service
NCT03638895COMPLETEDNA
51 participants
INTERVENTIONAL
Liverpool, United Kingdom
Started: Nov 28, 2018
Cost-effectiveness Study of a Lifestyle Change Program for the Treatment of OSA and Obesity: Hospital-Primary Care.
NCT04296721COMPLETEDNA
90 participants
INTERVENTIONAL
L'Hospitalet de Llobregat, Spain
Started: Jan 1, 2019
Recruitment Strategies Comparing Different Strategies in Sleep Apnea and Prediabetes
NCT03984058COMPLETEDNA
1 participants
INTERVENTIONAL
Baltimore, United States
Started: Oct 1, 2019
Effects of CPAP on Cognitive Function, Neurocognitive Architecture and Function in Patients With OSA: The SMOSAT Trial
NCT02886156COMPLETEDNA
148 participants
INTERVENTIONAL
Shanghai, China
Started: Apr 4, 2017