Ibuprofen
Treatment for Tension Headache
Typical Dosage: 200-400 mg every 4-6 hours, max 1200 mg/day (OTC)
Effectiveness
68%
Safety Score
75%
Clinical Trials
5
Participants
75K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
200-400 mg every 4-6 hours, max 1200 mg/day (OTC)
Time to Effect
30-60 minutes
Treatment Duration
As needed for acute episodes
Evidence Quality
HIGHNumber Needed to Treat (NNT)
7(Treat 7 patients to see 1 additional successful outcome)
Confidence Score
89%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$1,000
Side Effect Mgmt:$10
Total Annual:$1,040
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.03
Outcome-Based Costs
Cost per Responder
$61.54
Ibuprofen Outcomes
for Tension Headache
Efficacy Outcomes
Overall Effectiveness
+68%
Response Rate
+65%
Common Side Effects
Dyspepsia
+15%
Nausea
+6%
Abdominal pain
+6%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
3 completed trials for Ibuprofen in Tension Headache
Placebo and Active Controlled, Double Dummy Study to Compare Efficacy of Aspirin and Ibuprofen in Treatment of Episodic Tension-type Headache
NCT01464983COMPLETEDPHASE4
1.11K participants
INTERVENTIONAL
Reading, United Kingdom +10 more
Started: Jan 1, 2004
Ibuprofen Sodium Tension Headache Study
NCT01362491COMPLETEDPHASE3
226 participants
INTERVENTIONAL
Philadelphia, United States
Started: Jun 1, 2011
Study Evaluating A Novel Ibuprofen Formulation In Episodic Tension-Type Headache
NCT01077973COMPLETEDPHASE3
200 participants
INTERVENTIONAL
Started: Mar 1, 2010