Active Surveillance (for Stage I)
Treatment for Testicular Cancer
Typical Dosage: Close monitoring (imaging, tumor markers, physical exam)
Effectiveness
95%
Safety Score
95%
Clinical Trials
6
Participants
30K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
Close monitoring (imaging, tumor markers, physical exam)
Time to Effect
Ongoing strategy
Treatment Duration
5-10 years
Evidence Quality
HIGHConfidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$3,000
Side Effect Mgmt:$100
Total Annual:$3,100
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$5,000/QALY
QALYs Gained
20
Comparison vs Primary RPLND (for Stage I NSGCT)
Cost Difference
$-30,000/year
Less expensive
QALY Difference
+0.05 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Active Surveillance (for Stage I) Outcomes
for Testicular Cancer
Efficacy Outcomes
Overall Effectiveness
+95%
Remission Rate
+95%
Common Side Effects
Anxiety/Psychological stress
+60%
Need for subsequent treatment
+25%
Sources:
Active Clinical Trials
3 active trials recruiting for Active Surveillance (for Stage I) in Testicular Cancer
WATChmAN Virtual Testicular Cancer Clinic
NCT03360994ACTIVE NOT RECRUITINGNA
144 participants
INTERVENTIONAL
Toronto, Canada
Started: Dec 15, 2017
Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma
NCT03937843ACTIVE NOT RECRUITINGPHASE2
135 participants
INTERVENTIONAL
Berlin, Germany +18 more
Started: Jul 29, 2019
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
NCT03067181RECRUITINGPHASE3
1.78K participants
INTERVENTIONAL
Birmingham, United States +628 more
Started: May 25, 2017
Completed Clinical Trials
2 completed trials for Active Surveillance (for Stage I) in Testicular Cancer
Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors
NCT00053352COMPLETEDPHASE3
302 participants
INTERVENTIONAL
Birmingham, United States +125 more
Started: Nov 3, 2003
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
NCT00716976COMPLETEDPHASE3
131 participants
INTERVENTIONAL
Birmingham, United States +75 more
Started: Jun 23, 2008