Adjuvant Carboplatin (for Stage I Seminoma)
Treatment for Testicular Cancer
Typical Dosage: AUC 7 (one dose) or AUC 7 x 2 doses (3 weeks apart)
Effectiveness
88%
Safety Score
30%
Clinical Trials
1
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
30
DangerousModerateSafe
Treatment Details
Dosage Range
AUC 7 (one dose) or AUC 7 x 2 doses (3 weeks apart)
Time to Effect
Weeks (to prevent recurrence)
Treatment Duration
3-8 weeks (1-2 cycles)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
7(Treat 7 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
25(Treat 25 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$4,000
Monitoring:$2,000
Side Effect Mgmt:$1,000
Total Annual:$7,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$63,000/QALY
QALYs Gained
24
Comparison vs Active Surveillance
Cost Difference
+$3,900/year
More expensive
QALY Difference
+0.00 QALYs
Better outcomes
Dominance
No dominance
Adjuvant Carboplatin (for Stage I Seminoma) Outcomes
for Testicular Cancer
Efficacy Outcomes
Overall Effectiveness
+88%
Common Side Effects
Nausea/Vomiting
+60%
Myelosuppression (Thrombocytopenia)
+70%
Fatigue
+65%
Hair thinning
+25%
Active Clinical Trials
1 active trial recruiting for Adjuvant Carboplatin (for Stage I Seminoma) in Testicular Cancer
Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma
NCT03937843ACTIVE NOT RECRUITINGPHASE2
135 participants
INTERVENTIONAL
Berlin, Germany +18 more
Started: Jul 29, 2019