Radiation Therapy (for Seminoma)
Treatment for Testicular Cancer
Typical Dosage: 20-30 Gy in 10-15 fractions
Effectiveness
85%
Safety Score
25%
Clinical Trials
4
Participants
20K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
25
DangerousModerateSafe
Treatment Details
Dosage Range
20-30 Gy in 10-15 fractions
Time to Effect
Weeks to months
Treatment Duration
2-3 weeks (10-15 fractions)
Evidence Quality
MODERATENumber Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100
Monitoring:$2,000
Side Effect Mgmt:$1,000
Total Annual:$23,100
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$100,000/QALY
QALYs Gained
23
Comparison vs Adjuvant Carboplatin
Cost Difference
+$16,100/year
More expensive
QALY Difference
-0.05 QALYs
Worse outcomes
Dominance
No dominance
Radiation Therapy (for Seminoma) Outcomes
for Testicular Cancer
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+100%
Common Side Effects
Fatigue
+80%
Nausea/Vomiting
+60%
Diarrhea
+40%
Skin irritation
+60%
Secondary malignancies (long-term)
+3%
Infertility
+50%
Active Clinical Trials
3 active trials recruiting for Radiation Therapy (for Seminoma) in Testicular Cancer
Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma
NCT03937843ACTIVE NOT RECRUITINGPHASE2
135 participants
INTERVENTIONAL
Berlin, Germany +18 more
Started: Jul 29, 2019
THERApy De-escalation for TESTicular Cancer
NCT06309745RECRUITING
30 participants
OBSERVATIONAL
London, United Kingdom
Started: Jun 24, 2024
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
NCT03067181RECRUITINGPHASE3
1.78K participants
INTERVENTIONAL
Birmingham, United States +628 more
Started: May 25, 2017