DFDA

Meropenem

Treatment for Typhoid Fever

Typical Dosage: 1g IV every 8 hours for 7-14 days

Effectiveness
96%
Safety Score
70%
Clinical Trials
1
Participants
1.5K

Comparative Safety Scale(Higher is safer)

Cyanide☠ī¸
Meth💀
CigarettesđŸšŦ
Chemoâ˜ĸī¸
AlcoholđŸē
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
1g IV every 8 hours for 7-14 days
Time to Effect
2-4 days
Treatment Duration
7-14 days
Evidence Quality
MODERATE
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$750
Monitoring:$10,000
Side Effect Mgmt:$100
Total Annual:$10,850
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATE
ICER
$108,500/QALY
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$11,302
Cost per Remission
$11,793
Prescription Access Economics
Risk Assessment
Requires Monitoring
Yes
Needs lab work/checkups
Meropenem Outcomes

for Typhoid Fever

Efficacy Outcomes
Overall Effectiveness
+96%
Response Rate
+96%
Remission Rate
+92%
Common Side Effects
Injection site reactions
+7%
Diarrhea
+3%
Nausea
+2%
Seizures
+0.1%

Sources:

oup.com
oup.com
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
2 active trials recruiting for Meropenem in Typhoid Fever

COMPARISON OF SINGLE VERSUS COMBINATION DRUG THERAPY IN EXTENSIVELY DRUG RESISTANT SALMONELLA TYPHI IN TERMS OF TIME TO DEFERVESCENCE

NCT07641348NOT YET RECRUITINGNA
View Study
94 participants
INTERVENTIONAL
Lahore, Pakistan
Started: Jul 1, 2026

Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever

NCT07314281RECRUITINGPHASE4
View Study
40 participants
INTERVENTIONAL
Karachi, Pakistan
Started: Apr 22, 2025
Completed Clinical Trials
2 completed trials for Meropenem in Typhoid Fever

Comparison of Two Drugs Regimen in Treatment of Complicated Typhoid Fever in Children

NCT04154722COMPLETEDPHASE4
View Study
126 participants
INTERVENTIONAL
Karachi, Pakistan
Started: Jun 20, 2019

This Randomized Controlled Trial Evaluates the Comparative Efficacy of Intravenous Meropenem Alone Versus Intravenous Meropenem Combined With Oral Azithromycin in Children Aged 6 Months to Under 5 Years Diagnosed With Blood Culture-confirmed Extensively Drug-resistant Uncomplicated Typhoid Fever

NCT07445282COMPLETEDPHASE4
View Study
90 participants
INTERVENTIONAL
Rahim Yar Khan, Pakistan
Started: May 14, 2025