Prednisone
Treatment for Ulcerative Colitis
Typical Dosage: 40-60 mg/day, then tapered
Effectiveness
85%
Safety Score
50%
Clinical Trials
13
Participants
40K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe
Treatment Details
Dosage Range
40-60 mg/day, then tapered
Time to Effect
Days to 1 week
Treatment Duration
Short courses (8-12 weeks taper)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
2(Treat 2 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
8(Treat 8 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$125
Monitoring:$200
Side Effect Mgmt:$125
Total Annual:$450
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.12
Outcome-Based Costs
Cost per Responder
$562.5
Cost per Remission
$900
Prednisone Outcomes
for Ulcerative Colitis
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+80%
Remission Rate
+50%
Common Side Effects
Insomnia/Mood changes
+40%
Increased appetite/Weight gain
+40%
Fluid retention
+30%
Hyperglycemia
+15%
GI upset
+8%
Active Clinical Trials
4 active trials recruiting for Prednisone in Ulcerative Colitis
Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction for Inpatients and Outpatients With Acute Severe Ulcerative Colitis
NCT07258771NOT YET RECRUITINGPHASE4
110 participants
INTERVENTIONAL
Ann Arbor, United States
Started: Dec 1, 2025
Fecal Microbiota Transplantation for Ulcerative Colitis
NCT03804931RECRUITINGPHASE2, PHASE3
120 participants
INTERVENTIONAL
Guangzhou, China
Started: Jan 20, 2019
Feasibility Pilot Sequential Multiple Assignment Randomized Trial (SMART) for Acute Severe Ulcerative Colitis
NCT05867329RECRUITINGPHASE4
162 participants
INTERVENTIONAL
Ann Arbor, United States
Started: Sep 30, 2023
Determination of the Optimal Treatment Target in Ulcerative Colitis
NCT04259138ACTIVE NOT RECRUITINGPHASE4
672 participants
INTERVENTIONAL
Ypsilanti, United States +57 more
Started: Feb 18, 2020
Completed Clinical Trials
3 completed trials for Prednisone in Ulcerative Colitis
Predicting Response to Standardized Pediatric Colitis Therapy
NCT01536535COMPLETEDPHASE4
431 participants
INTERVENTIONAL
Los Angeles, United States +28 more
Started: Jul 10, 2012
Identifying Young Inflammatory Bowel Disease Patients at Risk for Herpes Zoster
NCT03553472COMPLETED
97 participants
OBSERVATIONAL
Madison, United States
Started: Jan 1, 2018
Efficacy of LiveSpo COLON as a Supportive Treatment for Inflammatory Bowel Disease (IBD)
NCT06637683COMPLETEDNA
60 participants
INTERVENTIONAL
Thái Bình, Vietnam
Started: Nov 15, 2019