DFDA

Ibuprofen

Treatment for Upper Respiratory Infections

Typical Dosage: 200-400mg every 4-6 hours (max 1200mg/day OTC)

Effectiveness
80%
Safety Score
75%
Clinical Trials
9
Participants
150K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
200-400mg every 4-6 hours (max 1200mg/day OTC)
Time to Effect
30-60 minutes
Treatment Duration
As needed, 3-7 days for URI symptoms
Evidence Quality
HIGH
Number Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
1500(Treat 1500 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$10
Monitoring:$600
Side Effect Mgmt:$0
Total Annual:$610
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
0.008
Outcome-Based Costs
Cost per Responder
$11.11
Ibuprofen Outcomes

for Upper Respiratory Infections

Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+90%
Common Side Effects
Stomach upset/nausea
+10%
Heartburn
+5%
Headache
+3%

Sources:

nih.gov
infectioncontroltoday.com
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Ibuprofen in Upper Respiratory Infections

Efficacy and Safety in the Combination of Ibuprofen / Loratadine Versus Ibuprofen Versus Loratadine

NCT06531707RECRUITINGPHASE3
View Study
177 participants
INTERVENTIONAL
Mexico City, Mexico
Started: May 20, 2024
Completed Clinical Trials
6 completed trials for Ibuprofen in Upper Respiratory Infections

The Efficacy and Safety of Dexibuprofen Syrup

NCT00812422COMPLETEDPHASE3
View Study
260 participants
INTERVENTIONAL
Seoul, South Korea +3 more
Started: Feb 1, 2008

Comparison of the Efficacy of Intravenous Paracetamol and Ibuprofen in the Treatment of Fever Due to Upper Respiratory Tract Infection

NCT03918135COMPLETEDPHASE4
View Study
200 participants
INTERVENTIONAL
Denizli, Turkey (Türkiye)
Started: Jan 1, 2019

Acute Sore Throat Pain Study

NCT01535079COMPLETEDPHASE2
View Study
186 participants
INTERVENTIONAL
Gières, France +3 more
Started: Feb 1, 2012

Ibuprofen Lozenge in Acute Sore Throat Pain

NCT01785862COMPLETEDPHASE3
View Study
427 participants
INTERVENTIONAL
Gières, France +13 more
Started: Feb 1, 2013

Bioequivalence Study of Ibuprofen 200 mg + Pseudoephedrine HCL 30 mg Tablets Under Fed Conditions

NCT01132222COMPLETEDPHASE1
View Study
34 participants
INTERVENTIONAL
Bangalore, India
Started: Sep 1, 2004

Bioequivalency Study of Ibuprofen 200 mg and Pseudoephedrine HCL 30 mg Tablets of Dr. Reddy's Under Fasting Conditions

NCT01131780COMPLETEDPHASE1
View Study
32 participants
INTERVENTIONAL
Bangalore, India
Started: Oct 1, 2004