Hypospadias Repair
Treatment for Urogenital Congenital Anomalies
Effectiveness
88%
Safety Score
70%
Clinical Trials
39
Participants
20K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate anatomical correction, functional healing and full recovery 6-12 months
Treatment Duration
Single surgery (uncomplicated), follow-up for several years
Evidence Quality
MODERATEConfidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$75
Monitoring:$750
Side Effect Mgmt:$500
Total Annual:$9,325
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.8
Outcome-Based Costs
Cost per Responder
$10,597
Comparison vs Watchful Waiting / No Treatment
Cost Difference
$0/year
Same cost
QALY Difference
+0.80 QALYs
Better outcomes
Dominance
No dominance
Hypospadias Repair Outcomes
for Urogenital Congenital Anomalies
Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+88%
Common Side Effects
Urethrocutaneous fistula
+10%
Urethral stricture
+5%
Meatal stenosis
+8%
Wound infection
+2%
Cosmetic dissatisfaction
+10%
Active Clinical Trials
5 active trials recruiting for Hypospadias Repair in Urogenital Congenital Anomalies
Distal Hypospadias Repair Outcome
NCT06700629NOT YET RECRUITINGNA
50 participants
INTERVENTIONAL
Asyut, Egypt +1 more
Started: Jan 1, 2025
Snodgrass Versus Grafted Snodgrass Repair in Narrow Urethral Plate in Distal Penile Hypospadias
NCT06405763RECRUITINGNA
50 participants
INTERVENTIONAL
Sohag, Egypt
Started: Dec 11, 2023
Modified TIP (Snodgrass) Using Interrupted Sutures in Hypospadias
NCT06180018NOT YET RECRUITINGNA
1 participants
INTERVENTIONAL
Asyut, Egypt
Started: Jan 1, 2024
Prophylactic Antibiotics or Placebo After Hypospadias Repair
NCT02096159ACTIVE NOT RECRUITINGNA
93 participants
INTERVENTIONAL
Chicago, United States +1 more
Started: Mar 1, 2014
Urethral Mobilisation Versus Mathieu Technique for Repair of Distal Hypospadias
NCT06705699NOT YET RECRUITINGNA
60 participants
INTERVENTIONAL
Started: Nov 25, 2024
Completed Clinical Trials
7 completed trials for Hypospadias Repair in Urogenital Congenital Anomalies
Can a Platelet-Rich Plasma Covering Layer Reduce Urethrocutaneous Fistula Rate After Distal Penile Hypospadias Repair Using the STAR Technique: A Randomized Controlled Trial
NCT07006922COMPLETEDNA
44 participants
INTERVENTIONAL
Giza, Egypt
Started: Jul 1, 2024
Isoamyl 2-Cyanoacrylate in the Urethro-cutaneous Fistula Repair
NCT04876976COMPLETEDPHASE2, PHASE3
40 participants
INTERVENTIONAL
Cairo, Egypt
Started: Jan 1, 2017
Redo Repair in Disrupted Hypospadias
NCT06187363COMPLETED
50 participants
OBSERVATIONAL
Alexandria, Egypt
Started: Jan 1, 2019
Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics
NCT05727969COMPLETEDNA
90 participants
INTERVENTIONAL
El Fayoum Qesm, Egypt
Started: Jan 15, 2023
Long Term Outcome of Hypospadias Repair
NCT02103712COMPLETED
170 participants
OBSERVATIONAL
Leeds, United Kingdom
Started: Oct 1, 2012
Antibiotic Use in Distal Hypospadias Repair
NCT03275519COMPLETEDNA
48 participants
INTERVENTIONAL
Little Rock, United States
Started: Jan 19, 2015
Modified Second Layer Repair for Distal Penile Hypospadias
NCT05253456COMPLETEDPHASE2
102 participants
INTERVENTIONAL
Cairo, Egypt
Started: Mar 1, 2018
Showing 20 of 42 total trials