Tamsulosin (Medical Expulsive Therapy)
Treatment for Urolithiasis
Typical Dosage: 0.4mg daily
Effectiveness
75%
Safety Score
65%
Clinical Trials
5
Participants
45K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
0.4mg daily
Time to Effect
Days for symptom relief, 2-4 weeks for stone passage
Treatment Duration
2-4 weeks
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$300
Side Effect Mgmt:$0
Total Annual:$350
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.3
Outcome-Based Costs
Cost per Responder
$500
Cost per Remission
$500
Tamsulosin (Medical Expulsive Therapy) Outcomes
for Urolithiasis
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+70%
Remission Rate
+70%
Common Side Effects
Retrograde ejaculation
+8%
Orthostatic hypotension
+4%
Dizziness
+3%
Headache
+2%
Active Clinical Trials
1 active trial recruiting for Tamsulosin (Medical Expulsive Therapy) in Urolithiasis
Comparison of Mirabegron and Tamsulosin for Ureteral Stone Expulsion
NCT07310797NOT YET RECRUITINGPHASE4
500 participants
INTERVENTIONAL
New Taipei City, Taiwan
Started: Jan 1, 2026
Completed Clinical Trials
2 completed trials for Tamsulosin (Medical Expulsive Therapy) in Urolithiasis
Medical Expulsive Therapy Post-SWL For Renal Stones
NCT05032287COMPLETEDNA
235 participants
INTERVENTIONAL
Al Mansurah, Egypt
Started: Sep 1, 2019
Medical Expulsive Therapy of Single Distal Ureteral Stones
NCT00831701COMPLETEDNA
100 participants
INTERVENTIONAL
Zurich, Switzerland
Started: Sep 1, 2006