DFDA

Tamsulosin (Medical Expulsive Therapy)

Treatment for Urolithiasis

Typical Dosage: 0.4mg daily

Effectiveness
75%
Safety Score
65%
Clinical Trials
5
Participants
45K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
MethπŸ’€
Cigarettes🚬
Chemo☒️
Alcohol🍺
MorphineπŸ’Š
AntibioticsπŸ’‰
TylenolπŸ’Š
ExerciseπŸƒ
WaterπŸ’§
65
DangerousModerateSafe
Treatment Details
Dosage Range
0.4mg daily
Time to Effect
Days for symptom relief, 2-4 weeks for stone passage
Treatment Duration
2-4 weeks
Evidence Quality
HIGH
Number Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$300
Side Effect Mgmt:$0
Total Annual:$350
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
0.3
Outcome-Based Costs
Cost per Responder
$500
Cost per Remission
$500
Tamsulosin (Medical Expulsive Therapy) Outcomes

for Urolithiasis

Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+70%
Remission Rate
+70%
Common Side Effects
Retrograde ejaculation
+8%
Orthostatic hypotension
+4%
Dizziness
+3%
Headache
+2%

Sources:

nih.gov
auajournals.org
auajournals.org

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
2 active trials recruiting for Tamsulosin (Medical Expulsive Therapy) in Urolithiasis

L-Citrulline Versus Tamsulosin for Medical Expulsive Therapy of Distal Ureteral Stones

NCT07617909RECRUITINGPHASE2
View Study
120 participants
INTERVENTIONAL
BanΔ« Suwayf, Egypt
Started: May 6, 2026

Comparison of Mirabegron and Tamsulosin for Ureteral Stone Expulsion

NCT07310797RECRUITINGPHASE4
View Study
500 participants
INTERVENTIONAL
New Taipei City, Taiwan
Started: Feb 13, 2026
Completed Clinical Trials
2 completed trials for Tamsulosin (Medical Expulsive Therapy) in Urolithiasis

Medical Expulsive Therapy Post-SWL For Renal Stones

NCT05032287COMPLETEDNA
View Study
235 participants
INTERVENTIONAL
Al Mansurah, Egypt
Started: Sep 1, 2019

Medical Expulsive Therapy of Single Distal Ureteral Stones

NCT00831701COMPLETEDNA
View Study
100 participants
INTERVENTIONAL
Zurich, Switzerland
Started: Sep 1, 2006