Thiazide Diuretics (e.g., Hydrochlorothiazide for Prevention)
Treatment for Urolithiasis
Typical Dosage: 12.5-50mg daily
Effectiveness
70%
Safety Score
68%
Clinical Trials
60
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
68
DangerousModerateSafe
Treatment Details
Dosage Range
12.5-50mg daily
Time to Effect
Weeks to months for optimal urinary parameters, long-term for prevention
Treatment Duration
Lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
8(Treat 8 patients to see 1 additional serious adverse event)
Confidence Score
92%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$300
Side Effect Mgmt:$70
Total Annual:$400
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$-30,000/QALY
QALYs Gained
1.5
Outcome-Based Costs
Cost per Responder
$667
Thiazide Diuretics (e.g., Hydrochlorothiazide for Prevention) Outcomes
for Urolithiasis
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+60%
Common Side Effects
Hypokalemia
+25%
Hyperuricemia
+15%
Hyperglycemia
+10%
Dizziness/Orthostatic hypotension
+8%
Fatigue
+5%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov