Acyclovir
Treatment for Varicella And Herpes Zoster
Typical Dosage: 800mg five times daily for 7-10 days
Effectiveness
85%
Safety Score
68%
Clinical Trials
17
Participants
30K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
68
DangerousModerateSafe
Treatment Details
Dosage Range
800mg five times daily for 7-10 days
Time to Effect
24-48 hours
Treatment Duration
7-10 days
Evidence Quality
HIGHNumber Needed to Treat (NNT)
15(Treat 15 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
1000(Treat 1000 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$100
Side Effect Mgmt:$10
Total Annual:$140
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.03
Outcome-Based Costs
Cost per Responder
$200
Cost per Remission
$159
Acyclovir Outcomes
for Varicella And Herpes Zoster
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+70%
Remission Rate
+88%
Common Side Effects
Nausea
+10%
Headache
+10%
Vomiting
+5%
Diarrhea
+3%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
12 completed trials for Acyclovir in Varicella And Herpes Zoster
Efficacy of Oral Famciclovir Versus Aciclovir Treatment in Patients With Herpes Zoster
NCT01327144COMPLETEDPHASE3
177 participants
INTERVENTIONAL
Porto Alegre, Brazil +4 more
Started: Jun 1, 2012
Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes Zoster
NCT02151240COMPLETEDPHASE4
94 participants
INTERVENTIONAL
Beijing, China
Started: May 1, 2014
A Study Exploring Efficacy of Peginterferon in Patients With Herpes Zoster
NCT05492591COMPLETEDPHASE2
50 participants
INTERVENTIONAL
Nanjing, China
Started: Oct 11, 2022
A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster
NCT00831103COMPLETEDPHASE2
373 participants
INTERVENTIONAL
Houston, United States
Started: Nov 1, 2007
Bioequivalency Study of Valacyclovir Hydrochloride 1000 mg Under Fasting Conditions
NCT01132729COMPLETEDNA
48 participants
INTERVENTIONAL
Fargo, United States
Started: Sep 1, 2006
Bioequivalency Study of Valacyclovir Hydrochloride 1000 mg Under Fed Conditions
NCT01132716COMPLETEDNA
48 participants
INTERVENTIONAL
Fargo, United States
Started: Sep 1, 2006
Palatability Testing of a New Paediatric Formulation of Valacyclovir
NCT01682109COMPLETEDPHASE4
41 participants
INTERVENTIONAL
Nijmegen, Netherlands
Started: Sep 1, 2012
Bioequivalence Study in Healthy Volunteers of a New Paediatric Formulation of Valacyclovir
NCT01689285COMPLETEDPHASE1
16 participants
INTERVENTIONAL
Nijmegen, Netherlands
Started: Dec 1, 2013
Reduction of Postherpetic Neuralgia in Herpes Zoster
NCT01250561COMPLETEDNA
133 participants
INTERVENTIONAL
Houston, United States
Started: Feb 1, 2002
Stellate Ganglion Block in Herpes Zoster
NCT04188327COMPLETEDNA
208 participants
INTERVENTIONAL
Tanta, Egypt +2 more
Started: May 1, 2020
Erector Spinae Plane Block in Post-herpetic Neuralgia
NCT04546334COMPLETEDNA
90 participants
INTERVENTIONAL
Tanta, Egypt
Started: Sep 26, 2020
A Safety And Tolerability Study Of Valaciclovir Oral Suspension In Infants And Children
NCT00297206COMPLETEDPHASE1
36 participants
INTERVENTIONAL
Birmingham, United States +12 more
Started: Jan 25, 2003